Literature DB >> 16572573

Safety of gadolinium during pregnancy.

Facundo Garcia-Bournissen1, Alon Shrim, Gideon Koren.   

Abstract

QUESTION: A pregnant patient who underwent magnetic resonance imaging (MRI) because of an acute abdomen, was told that MRI contrast agents (ie, gadolinium-based contrast agents) are contraindicated during pregnancy. What is the risk to her baby? ANSWER: Current radiology practices and recommendations discourage the use of gadolinium-based contrast agents during pregnancy because their safety for the fetus has not yet been proven. In line, however, with the European Society of Radiology guidelines and based on the available evidence, gadolinium-based contrast agents appear to be safe in pregnancy. Gadolinium use should be considered when the diagnostic study is important for the health of the mother.

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Year:  2006        PMID: 16572573      PMCID: PMC1479713     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  19 in total

1.  Cardiovascular effects caused by rapid administration of gadoversetamide injection in anesthetized dogs.

Authors:  J H Wible; K P Galen; J K Wojdyla
Journal:  Invest Radiol       Date:  2001-05       Impact factor: 6.016

Review 2.  Fast MR imaging in obstetrics.

Authors:  Masako Nagayama; Yuji Watanabe; Akira Okumura; Yoshiki Amoh; Satoru Nakashita; Yoshihiro Dodo
Journal:  Radiographics       Date:  2002 May-Jun       Impact factor: 5.333

Review 3.  MR imaging of maternal diseases of the abdomen and pelvis during pregnancy and the immediate postpartum period.

Authors:  John R Leyendecker; Vladislav Gorengaut; Jeffrey J Brown
Journal:  Radiographics       Date:  2004 Sep-Oct       Impact factor: 5.333

4.  Summary of preclinical safety evaluation of gadoteridol injection.

Authors:  R A Soltys
Journal:  Invest Radiol       Date:  1992-08       Impact factor: 6.016

5.  The use of iodinated and gadolinium contrast media during pregnancy and lactation.

Authors:  Judith A W Webb; Henrik S Thomsen; Sameh K Morcos
Journal:  Eur Radiol       Date:  2004-12-18       Impact factor: 5.315

6.  Inadvertent i.v. administration of gadopentetate dimeglumine during early pregnancy.

Authors:  F Barkhof; R J Heijboer; P R Algra
Journal:  AJR Am J Roentgenol       Date:  1992-05       Impact factor: 3.959

7.  Gadolinium-enhanced MR imaging in the differential diagnosis of placenta accreta and placenta percreta.

Authors:  J M Palacios Jaraquemada; C Bruno
Journal:  Radiology       Date:  2000-08       Impact factor: 11.105

8.  Toxicological safety evaluation of gadobenate dimeglumine 0.5 M solution for injection (MultiHance), a new magnetic resonance imaging contrast medium.

Authors:  A Morisetti; S Bussi; P Tirone; C de Haën
Journal:  J Comput Assist Tomogr       Date:  1999-11       Impact factor: 1.826

9.  Use of magnetic resonance imaging and ultrasound in the antenatal diagnosis of placenta accreta.

Authors:  Garrett Lam; Jeffrey Kuller; Michael McMahon
Journal:  J Soc Gynecol Investig       Date:  2002 Jan-Feb

10.  Gadolinium-DTPA transplacental transfer and distribution in fetal tissue in rabbits.

Authors:  Z Novak; A S Thurmond; P L Ross; M K Jones; K L Thornburg; R W Katzberg
Journal:  Invest Radiol       Date:  1993-09       Impact factor: 6.016

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  16 in total

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Authors:  Brian A Hogan; Carl J Brown; Jacqueline A Brown
Journal:  Emerg Radiol       Date:  2007-07-03

2.  Guidelines for diagnosis, treatment, and use of laparoscopy for surgical problems during pregnancy: this statement was reviewed and approved by the Board of Governors of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), September 2007. It was prepared by the SAGES Guidelines Committee.

Authors:  Hori Yumi
Journal:  Surg Endosc       Date:  2008-02-21       Impact factor: 4.584

Review 3.  Diagnosis and laparoscopic treatment of surgical diseases during pregnancy: an evidence-based review.

Authors:  Heidi Jackson; Steven Granger; Raymond Price; Michael Rollins; David Earle; William Richardson; Robert Fanelli
Journal:  Surg Endosc       Date:  2008-06-14       Impact factor: 4.584

4.  Guidelines for diagnosis, treatment, and use of laparoscopy for surgical problems during pregnancy.

Authors:  Jonathan Pearl; Raymond Price; William Richardson; Robert Fanelli
Journal:  Surg Endosc       Date:  2011-09-23       Impact factor: 4.584

5.  Organ retention of gadolinium in mother and pup mice: effect of pregnancy and type of gadolinium-based contrast agents.

Authors:  Khongorzul Erdene; Takahito Nakajima; Satomi Kameo; Miski Aghnia Khairinisa; Oyunbold Lamid-Ochir; Amartuvshin Tumenjargal; Noriyuki Koibuchi; Hiroshi Koyama; Yoshito Tsushima
Journal:  Jpn J Radiol       Date:  2017-07-20       Impact factor: 2.374

6.  SAGES guidelines for the use of laparoscopy during pregnancy.

Authors:  Jonathan P Pearl; Raymond R Price; Allison E Tonkin; William S Richardson; Dimitrios Stefanidis
Journal:  Surg Endosc       Date:  2017-06-22       Impact factor: 4.584

7.  Pregnancy and Marfan syndrome.

Authors:  Sorel Goland; Uri Elkayam
Journal:  Ann Cardiothorac Surg       Date:  2017-11

Review 8.  Migraine in pregnancy and lactation.

Authors:  Paru S David; Juliana M Kling; Amaal J Starling
Journal:  Curr Neurol Neurosci Rep       Date:  2014-04       Impact factor: 5.081

9.  Diffusion-weighted MRI for Unenhanced Breast Cancer Screening.

Authors:  Nita Amornsiripanitch; Sebastian Bickelhaupt; Hee Jung Shin; Madeline Dang; Habib Rahbar; Katja Pinker; Savannah C Partridge
Journal:  Radiology       Date:  2019-10-08       Impact factor: 11.105

10.  A case of maternal herpes simplex virus encephalitis during late pregnancy.

Authors:  Johann Sellner; Roberto Buonomano; Krassen Nedeltchev; Oliver Findling; Gerhard Schroth; Daniel V Surbek; Stephen L Leib
Journal:  Nat Clin Pract Neurol       Date:  2009-01
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