Literature DB >> 16571588

Inference of mental states in patients with Alzheimer's disease.

Deborah Zaitchik1, Elissa Koff, Hiram Brownell, Ellen Winner, Marilyn Albert.   

Abstract

INTRODUCTION: The ability to determine what someone thinks or knows often requires an individual to infer the mental state of another person, an ability typically referred to as one's "theory of mind". The present study tests this ability in patients with mild-to-moderate Alzheimer's disease (AD).
METHODS: Three theory of mind tests and three standardised neuropsychological tests were presented to a group of patients with AD (n = 25) and a group of healthy elderly controls (n = 15).
RESULTS: On the first two theory of mind tasks, the performance of the AD patients was nearly perfect and did not differ from that of the controls: AD patients showed no difficulties in either attributing a false belief to another person, or in recognising their own previous false beliefs. On the third theory of mind task, where the key information was embedded in a story narrative, AD patients per formed significantly worse than controls. However, their performance on this task was similar to the control condition, which used a similar story but which did not involve beliefs.
CONCLUSIONS: These results, as well as those involving correlations between the neuropsychological tests and performance on the third task, suggest that the AD patients' difficulty may be secondary to their cognitive impairments, rather than a primary impairment in theory of mind.

Entities:  

Year:  2004        PMID: 16571588     DOI: 10.1080/13546800344000246

Source DB:  PubMed          Journal:  Cogn Neuropsychiatry        ISSN: 1354-6805            Impact factor:   1.871


  6 in total

1.  Overlapping and non-overlapping brain regions for theory of mind and self reflection in individual subjects.

Authors:  Rebecca Saxe; Joseph M Moran; Jonathan Scholz; John Gabrieli
Journal:  Soc Cogn Affect Neurosci       Date:  2006-12       Impact factor: 3.436

2.  Comprehension of insincere communication in neurodegenerative disease: lies, sarcasm, and theory of mind.

Authors:  Tal Shany-Ur; Pardis Poorzand; Scott N Grossman; Matthew E Growdon; Jung Y Jang; Robin S Ketelle; Bruce L Miller; Katherine P Rankin
Journal:  Cortex       Date:  2011-09-01       Impact factor: 4.027

3.  Can theory of mind deficits be measured reliably in people with mild and moderate Alzheimer's dementia?

Authors:  Caroline Sm Choong; Gillian A Doody
Journal:  BMC Psychol       Date:  2013-12-05

Review 4.  Neurocognitive mechanisms of theory of mind impairment in neurodegeneration: a transdiagnostic approach.

Authors:  Cherie Strikwerda-Brown; Siddharth Ramanan; Muireann Irish
Journal:  Neuropsychiatr Dis Treat       Date:  2019-02-20       Impact factor: 2.570

5.  Association Between Social Cognition Changes and Resting State Functional Connectivity in Frontotemporal Dementia, Alzheimer's Disease, Parkinson's Disease, and Healthy Controls.

Authors:  Namita Multani; Foad Taghdiri; Cassandra J Anor; Brenda Varriano; Karen Misquitta; David F Tang-Wai; Ron Keren; Susan Fox; Anthony E Lang; Anne Catherine Vijverman; Connie Marras; Maria Carmela Tartaglia
Journal:  Front Neurosci       Date:  2019-11-22       Impact factor: 4.677

6.  The Role of Hub and Spoke Regions in Theory of Mind in Early Alzheimer's Disease and Frontotemporal Dementia.

Authors:  Beatrice Orso; Luigi Lorenzini; Dario Arnaldi; Nicola Girtler; Andrea Brugnolo; Elisa Doglione; Pietro Mattioli; Erica Biassoni; Federico Massa; Enrico Peira; Matteo Bauckneht; Maria I Donegani; Silvia Morbelli; Flavio Nobili; Matteo Pardini
Journal:  Biomedicines       Date:  2022-02-24
  6 in total

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