Literature DB >> 16569925

Pregnancy in a patient of Glanzmann's thrombasthenia.

Neena Malhotra1, Charu Chanana, Deepika Deka.   

Abstract

Glanzmann's thrombasthenia is a congenitally acquired platelet disorder with an autosomal recessive mode of inheritance. Though, quantitatively normal, the aggregation ability of platelets is reduced in this condition. Pregnancy and delivery are rare in these patients and have been associated with a high risk of severe post-partum hemorrhage. We describe a primigravida, who was diagnosed to have Glanzmann's thrombasthenia during adolescence. She developed secondary post-partum hemorrhage after an elective caesarean section, which was successfully managed by single donor platelet transfusion.

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Year:  2006        PMID: 16569925

Source DB:  PubMed          Journal:  Indian J Med Sci        ISSN: 0019-5359


  2 in total

1.  Glanzmann thrombasthenia in pregnancy: Optimising maternal and fetal outcomes.

Authors:  A Wijemanne; I Watt-Coote; S Austin
Journal:  Obstet Med       Date:  2016-08-03

2.  Menstrual and obstetrical bleeding in women with inherited platelet receptor defects-A systematic review.

Authors:  Marieke C Punt; Pauline C E Schuitema; Kitty W M Bloemenkamp; Idske C L Kremer Hovinga; Karin P M van Galen
Journal:  Haemophilia       Date:  2020-01-31       Impact factor: 4.287

  2 in total

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