Literature DB >> 16569078

Identification of steviol glucuronide in human urine.

Jan M C Geuns1, Johan Buyse, Annelies Vankeirsbilck, Elisabeth H M Temme, Frans Compernolle, Suzanne Toppet.   

Abstract

Stevioside (250 mg capsules) was given three times daily to 10 healthy subjects. Steviol glucuronide (steviol 19-O-beta-D-glucopyranosiduronic acid; MM, 494.58; melting point, 198-199 degrees C) was characterized in the 24 h urine as the only excretion product of oral stevioside by MS, NMR, IR, and UV spectroscopy. This is the first report on the unambiguous identification of steviol glucuronide in human urine.

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Year:  2006        PMID： 16569078     DOI： 10.1021/jf052693e

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  8 in total

1.  Stevioside Counteracts Beta-Cell Lipotoxicity without Affecting Acetyl CoA Carboxylase.

Authors:  Jianguo Chen; Per Bendix Jeppesen; Iver Nordentoft; Kjeld Hermansen
Journal:  Rev Diabet Stud       Date:  2007-02-10

2.  Synthesis of ent-kaurane diterpene monoglycosides.

Authors:  Venkata Sai Prakash Chaturvedula; Josef Klucik; Mani Upreti; Indra Prakash
Journal:  Molecules       Date:  2011-10-03       Impact factor: 4.411

3.  Steviol glucuronide, a metabolite of steviol glycosides, potently stimulates insulin secretion from isolated mouse islets: Studies in vitro.

Authors:  Wenqian Gu; Andreas Rebsdorf; Camilla Anker; Søren Gregersen; Kjeld Hermansen; Jan M C Geuns; Per Bendix Jeppesen
Journal:  Endocrinol Diabetes Metab       Date:  2019-09-06

Review 4.  Plausible Biological Interactions of Low- and Non-Calorie Sweeteners with the Intestinal Microbiota: An Update of Recent Studies.

Authors:  Julio Plaza-Diaz; Belén Pastor-Villaescusa; Ascensión Rueda-Robles; Francisco Abadia-Molina; Francisco Javier Ruiz-Ojeda
Journal:  Nutrients       Date:  2020-04-21       Impact factor: 5.717

5.  Characterization of Microbial Degradation Products of Steviol Glycosides.

Authors:  Gert Steurs; Nico Moons; Luc Van Meervelt; Boudewijn Meesschaert; Wim Michel De Borggraeve
Journal:  Molecules       Date:  2021-11-16       Impact factor: 4.411

6.  Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial.

Authors:  Caroline Simoens; Koenraad Philippaert; Caroline Wuyts; Séverine Goscinny; Els Van Hoeck; Joris Van Loco; Jaak Billen; Jan de Hoon; Els Ampe; Roman Vangoitsenhoven; Ann Mertens; Rudi Vennekens; Bart Van der Schueren
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2022-09-03       Impact factor: 2.569

Review 7.  Biomarkers of intake for coffee, tea, and sweetened beverages.

Authors:  Joseph A Rothwell; Francisco Madrid-Gambin; Mar Garcia-Aloy; Cristina Andres-Lacueva; Caomhan Logue; Alison M Gallagher; Carina Mack; Sabine E Kulling; Qian Gao; Giulia Praticò; Lars O Dragsted; Augustin Scalbert
Journal:  Genes Nutr       Date:  2018-07-04       Impact factor: 5.523

Review 8.  Approaches toward the Separation, Modification, Identification and Scale up Purification of Tetracyclic Diterpene Glycosides from Stevia rebaudiana (Bertoni) Bertoni.

Authors:  Wilmer H Perera; James D McChesney
Journal:  Molecules       Date:  2021-03-29       Impact factor: 4.411
  8 in total

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