Literature DB >> 16567109

Septal anterior ventricular exclusion operation (Pacopexy) for ischemic dilated cardiomyopathy: treat form not disease.

Tadashi Isomura1, Taiko Horii, Hisayoshi Suma, Gerald D Buckberg.   

Abstract

OBJECTIVE: Restoration of left ventricle size and shape is an effective surgical procedure in patients with dilated cardiomyopathy. This report defines early and intermediate results following the reshaping of the left ventricle from spherical to ellipsoid configuration in patients with ischemic cardiomyopathy, employing a technique for LV restoration (LVR) that uses form rather than disease as the endpoint for oblique patch placement.
METHODS: Between 1998 and 2004, a cohort of 83 patients with dilated ischemic cardiomyopathy underwent an operation to reshape the left ventricle. In 54 patients the Dor procedure was done, and 29 underwent the septal anterior ventricular exclusion (SAVE) procedure to emphasize the elliptical shape, whereby patch placement followed an oblique trajectory between the LV apex and septum below the aortic valve. Ventricular form, rather than the disease scar marked the suture placement site endpoint to create an ellipse. The mean age was 58+/-27, but SAVE patients had larger end systolic volume index (135+/-38 vs 95+/-25). Overall preoperative NYHA functional class III was in 69% and IV in 31 patients, but more SAVE patients were in class IV (38% vs 28%). The procedures were elective in 72 and emergent in 11, with similar entry criteria for each procedure.
RESULTS: In combination with LVR operation, mitral surgery was performed in 49/83 and tricuspid annuloplasty in 23/83 patients, but these procedures were more common after SAVE (59% vs 44% and 45% vs 19%, respectively), because of larger LV volumes in SAVE patients; 2.8+/-1.3 coronary artery bypass grafts were used. Perioperative use of IABP or LVAD was 15 and 1, respectively in 83 patients. Hospital death was in 1/11 or 9% after emergent operations and 3/72 or 4% in elective procedures, with no difference between groups. After discharge from the hospital, NYHA class improved to class I or II in 57 patients, class III/IV in 14 patients, with 10 late deaths. The 5-year survival rate after the elective operation was 80.3% in SAVE and with elective operation and 77.4% in the Dor procedure.
CONCLUSION: The SAVE or Pacopexy technique is easy to reshape the dilated left ventricle from spherical to ellipsoid form after the LVR, and the resultant improved configuration may contribute to the overall results for patients with ischemic dilated cardiomyopathy.

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Year:  2006        PMID: 16567109     DOI: 10.1016/j.ejcts.2006.03.008

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  17 in total

1.  Significance of preoperative right ventricular function on mid-term outcomes after surgical ventricular restoration for ischemic cardiomyopathy.

Authors:  Koji Furukawa; Mitsuhiro Yano; Masanori Nishimura; Eisaku Nakamura; Nozomi Watanabe; Shun Nishino; Kunihide Nakamura
Journal:  Gen Thorac Cardiovasc Surg       Date:  2019-04-09

Review 2.  Surgical ventricular restoration for the treatment of heart failure.

Authors:  Gerald Buckberg; Constantine Athanasuleas; John Conte
Journal:  Nat Rev Cardiol       Date:  2012-11-13       Impact factor: 32.419

3.  Basic fibroblast growth factor attenuates left-ventricular remodeling following surgical ventricular restoration in a rat ischemic cardiomyopathy model.

Authors:  Atsushi Nagasawa; Hidetoshi Masumoto; Shigeki Yanagi; Naoki Kanemitsu; Tadashi Ikeda; Yasuhiko Tabata; Kenji Minatoya
Journal:  Gen Thorac Cardiovasc Surg       Date:  2019-08-13

4.  The Pacopexy procedure for left ventricular aneurysm: a 10-year clinical experience.

Authors:  Huimin Cui; Yuanbin Wu; Shixiong Wei; Changqing Gao; Shengli Jiang
Journal:  Surg Today       Date:  2019-09-13       Impact factor: 2.549

Review 5.  Posterior ventricular restoration treatment for heart failure: a review, past, present and future aspects.

Authors:  Tadashi Isomura; Yasuhisa Fukada; Takuya Miyazaki; Minoru Yoshida; Akimasa Morisaki; Masahiro Endo
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-02-04

6.  Effect of preoperative left ventricular diastolic dysfunction on mid-term outcomes after surgical ventricular restoration for ischemic cardiomyopathy.

Authors:  Koji Furukawa; Mitsuhiro Yano; Eisaku Nakamura; Masakazu Matsuyama; Masanori Nishimura; Katsuya Kawagoe; Kunihide Nakamura
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-04-04

7.  Mid-term results of mitral valve repair for ischemic mitral regurgitation adjusted according to the degree of remodeling progression.

Authors:  Koji Furukawa; Mitsuhiro Yano; Eisaku Nakamura; Masanori Nishimura; Kunihide Nakamura
Journal:  Gen Thorac Cardiovasc Surg       Date:  2018-08-25

8.  Surgical Ventricular Restoration: An Operation to Reverse Remodeling - Clinical Application (Part II).

Authors:  Ganesh Shanmugam; Imtiaz S Ali
Journal:  Curr Cardiol Rev       Date:  2009-11

9.  Surgical ventricular restoration based on evaluation of myocardial viability with delayed-enhanced magnetic resonance imaging.

Authors:  Mitsugu Ogawa; Kiyoshi Doi; Yoshiaki Yamada; Atsushi Fukumoto; Kazunari Okawa; Tamotsu Kan'bara; Keitarou Koushi; Hirotshi Itoh; Tsunehiko Nishimura; Hitoshi Yaku
Journal:  Gen Thorac Cardiovasc Surg       Date:  2007-04

10.  A new surgical ventricular restoration technique to reset residual myocardium's fiber orientation: the "KISS" procedure.

Authors:  Marco Cirillo
Journal:  Ann Surg Innov Res       Date:  2009-06-23
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