| Literature DB >> 16566931 |
Gary N Clarke1, Scott G McCoombe, Roger V Short.
Abstract
The aim of this study was to evaluate the sperm-immobilizing properties of lemon juice to determine if they are consistent with its traditional contraceptive use. It was found that lemon juice supernatant (LJS) has high osmolality (550-60 mOsm) and low pH (2.2-2.6) and that addition of LJS to semen to give a final concentration of 20% v/v reduced the pH from around 8.4 to 4.1. This acidification was associated with irreversible cessation of all sperm movements within 1 minute. In conclusion, lemon juice should be further evaluated for acceptability, safety, and efficacy as a topical vaginal contraceptive agent.Entities:
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Year: 2006 PMID: 16566931 DOI: 10.1016/j.fertnstert.2005.10.040
Source DB: PubMed Journal: Fertil Steril ISSN: 0015-0282 Impact factor: 7.329