| Literature DB >> 16564721 |
S Biver1, S Scohy, J Szpirer, C Szpirer, B André, A-M Marini.
Abstract
Ammonium excretion into urine is a major process essential to the regulation of acid-base homeostasis. We have shown that Rh-type proteins, including renal RhCG, belong to the Mep/Amt family of ammonium transporters and promote bi-directional ammonium transport upon heterologous expression in yeast. To study the physiological role of RhCG and to test a potential function in ammonium excretion, we have generated mice bearing an invalidation of the corresponding gene.Entities:
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Year: 2006 PMID： 16564721 DOI： 10.1016/j.tracli.2006.03.003
Source DB: PubMed Journal: Transfus Clin Biol ISSN： 1246-7820 Impact factor: 1.406