Literature DB >> 16564533

Use of ultra-performance liquid chromatography in pharmaceutical development.

Stephen A C Wren1, Pierre Tchelitcheff.   

Abstract

Ultra-performance liquid chromatography (UPLC) has been investigated as an alternative to HPLC for the analysis of pharmaceutical development compounds. We present data on three compounds showing that significant reductions in separation time can be achieved without compromising the separation quality. Results from precision and comparative studies indicate that UPLC is a suitable technique for routine pharmaceutical analysis.

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Year:  2006        PMID： 16564533     DOI： 10.1016/j.chroma.2006.02.052

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  14 in total

1.  Development of Narrow-Bore C18 Column for Fast Separation of Peptides and Proteins in High-Performance Liquid Chromatography.

Authors:  Ashraf Ali; Sarah Alharthi; Nora Hamad Al-Shaalan; Eman Y Santali
Journal:  Polymers (Basel)       Date:  2022-06-25       Impact factor: 4.967

2.  UHPLC: The Greening Face of Liquid Chromatography.

Authors:  Judyta Cielecka-Piontek; Przemysław Zalewski; Anna Jelińska; Piotr Garbacki
Journal:  Chromatographia       Date:  2013-03-07       Impact factor: 2.044

3.  Comparison of UHPLC and HPLC in benzodiazepines analysis of postmortem samples: a case-control study.

Authors:  Behnam Behnoush; Ardeshir Sheikhazadi; Elham Bazmi; Akbar Fattahi; Elham Sheikhazadi; Seyed Hossein Saberi Anary
Journal:  Medicine (Baltimore)       Date:  2015-04       Impact factor: 1.889

4.  Simultaneous quantitation of chloroquine and primaquine by UPLC-DAD and comparison with a HPLC-DAD method.

Authors:  Tiago A Miranda; Pedro H R Silva; Gerson A Pianetti; Isabela C César
Journal:  Malar J       Date:  2015-01-28       Impact factor: 2.979

5.  Impurity profiling and in-process testing of drugs for injection by fast liquid chromatography.

Authors:  Marie-Josée Rocheleau; Elaine Larouche; Cristina Salamu; Mihaela Curca
Journal:  J Pharm Anal       Date:  2012-07-24

6.  Implementation of a single quad MS detector in routine QC analysis of peptide drugs.

Authors:  Matthias D'Hondt; Bert Gevaert; Evelien Wynendaele; Bart De Spiegeleer
Journal:  J Pharm Anal       Date:  2015-09-26

Review 7.  A holistic strategy for quality and safety control of traditional Chinese medicines by the "iVarious" standard system.

Authors:  Anzhen Chen; Lei Sun; Hang Yuan; Aiying Wu; Jingguang Lu; Shuangcheng Ma
Journal:  J Pharm Anal       Date:  2017-07-14

8.  Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, its Related Substances, and Degradation Products.

Authors:  Pallavi Vukkum; Girish R Deshpande; J Moses Babu; R Muralikrishna; Pavani Jagu
Journal:  Sci Pharm       Date:  2012-07-27

9.  Validation of simultaneous quantitative method of HIV protease inhibitors atazanavir, darunavir and ritonavir in human plasma by UPLC-MS/MS.

Authors:  Tulsidas Mishra; Pranav S Shrivastav
Journal:  ScientificWorldJournal       Date:  2014-01-23

10.  UPLC-PDA determination of paeoniflorin in rat plasma following the oral administration of Radix Paeoniae Alba and its effects on rats with collagen-induced arthritis.

Authors:  Dan Wu; Jiang Chen; Hao Zhu; Xin-Gui Xiong; Qing-Hua Liang; Yang Zhang; Yong Zhang; Yang Wang; Bo Yang; Xi Huang
Journal:  Exp Ther Med       Date:  2013-10-23       Impact factor: 2.447
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