Literature DB >> 16564195

Spondylarthropathy striking prevalence in a 19th-20th century Portuguese collection.

Sophie Martin-Dupont1, Eugénia Cunha, Daniel Rougé, Eric Crubézy.   

Abstract

UNLABELLED: The concept of spondylarthropathy (SPAP) covers a series of pathologies sharing a common genetic basis and infectious triggers.
OBJECTIVES: To present and discuss the prevalence of SPAP in the Coimbra identified skeletal collection, a 19th-20th century Portuguese sample.
MATERIALS AND METHODS: Each of the 505 individuals was macroscopically examined; each joint being assessed for degenerative, inflammatory, ankylosing, entesopathic, traumatic, congenital, infectious, or associated lesions. For the diagnosis of SPAP, besides the criteria proposed by Rogers and Rothschild, it was also applied a new set of criteria established by Martin-Dupont. Associated and differential diagnoses were also discussed.
RESULTS: Using these latter criteria, SPAP was definitely diagnosed in 34 individuals (6.7%), mostly women and elderly individuals. Furthermore, SPAP was diagnosed as probable in 32 (6.3%) and could not be excluded in 98 skeletons (19.4%). Except for the third category, the results were close to those obtained when using the arguments of others authors. DISCUSSION: The specificity of each criterion is discussed, and the results are precautiously compared with other studies both from past and contemporary samples. Graduating the diagnosis as certain, probable or unexcluded, seems to us of interest, leading to etiological discussion as in clinical practice.
CONCLUSION: The high prevalence of SPAP achieved for the Portuguese collection might be explained by high exposure to infectious triggers.

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Year:  2005        PMID: 16564195     DOI: 10.1016/j.jbspin.2005.05.005

Source DB:  PubMed          Journal:  Joint Bone Spine        ISSN: 1297-319X            Impact factor:   4.929


  2 in total

1.  The coexistence of ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis--a postmortem diagnosis.

Authors:  Xavier Jordana; Ignasi Galtés; Ana Rita Couto; Luís Gales; Margarida Damas; Manuela Lima; Jácome Bruges-Armas
Journal:  Clin Rheumatol       Date:  2008-12-17       Impact factor: 2.980

2.  The influence of life history and sexual dimorphism on entheseal changes in modern humans and African great apes.

Authors:  Marco Milella
Journal:  PLoS One       Date:  2014-09-24       Impact factor: 3.240

  2 in total

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