Literature DB >> 16564060

Toxin profile of Alexandrium ostenfeldii (Dinophyceae) from the Northern Adriatic Sea revealed by liquid chromatography-mass spectrometry.

Patrizia Ciminiello1, Carmela Dell'Aversano, Ernesto Fattorusso, Silvana Magno, Luciana Tartaglione, Monica Cangini, Marinella Pompei, Franca Guerrini, Laurita Boni, Rossella Pistocchi.   

Abstract

This paper reports on the first occurrence of fairly high numbers of Alexandrium ostenfeldii along the Emilia Romagna coasts (Italy). Detailed liquid chromatography-mass spectrometry (LC-MS) analyses of the toxin profile were performed on a strain of the organism collected in November 2003, isolated during the event and grown in culture. Selected ion monitoring (SIM) and multiple reaction monitoring (MRM) experiments were carried out for detection of spirolides and paralytic shellfish poisoning (PSP) toxins. They revealed that the Adriatic A. ostenfeldii produces mainly spirolide 13-desmethyl C at levels of 3.7 pg/cell but not PSP toxins. Interestingly, low levels of some spirolide isomers that have not been reported so far in other strains of the dinoflagellate were also detected. This represents the first report of spirolide-type toxins in the Adriatic Sea.

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Year:  2006        PMID: 16564060     DOI: 10.1016/j.toxicon.2006.02.003

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  16 in total

Review 1.  Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.

Authors:  Craig E Stivala; Evelyne Benoit; Rómulo Aráoz; Denis Servent; Alexei Novikov; Jordi Molgó; Armen Zakarian
Journal:  Nat Prod Rep       Date:  2015-03       Impact factor: 13.423

2.  Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system.

Authors:  Laura P Rodríguez; Natalia Vilariño; Jordi Molgó; Rómulo Aráoz; M Carmen Louzao; Palmer Taylor; Todd Talley; Luis M Botana
Journal:  Anal Chem       Date:  2013-02-07       Impact factor: 6.986

3.  Coupling the Torpedo microplate-receptor binding assay with mass spectrometry to detect cyclic imine neurotoxins.

Authors:  Rómulo Aráoz; Suzanne Ramos; Franck Pelissier; Vincent Guérineau; Evelyne Benoit; Natalia Vilariño; Luis M Botana; Armen Zakarian; Jordi Molgó
Journal:  Anal Chem       Date:  2012-11-21       Impact factor: 6.986

4.  Use of biosensors as alternatives to current regulatory methods for marine biotoxins.

Authors:  Natalia Vilariño; Eva S Fonfría; M Carmen Louzao; Luis M Botana
Journal:  Sensors (Basel)       Date:  2009-11-24       Impact factor: 3.576

Review 5.  Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species.

Authors:  Rossella Pistocchi; Franca Guerrini; Laura Pezzolesi; Manuela Riccardi; Silvana Vanucci; Patrizia Ciminiello; Carmela Dell'Aversano; Martino Forino; Ernesto Fattorusso; Luciana Tartaglione; Anna Milandri; Marinella Pompei; Monica Cangini; Silvia Pigozzi; Elena Riccardi
Journal:  Mar Drugs       Date:  2012-01-17       Impact factor: 6.085

Review 6.  Emergent toxins in North Atlantic temperate waters: a challenge for monitoring programs and legislation.

Authors:  Marisa Silva; Vijaya K Pratheepa; Luis M Botana; Vitor Vasconcelos
Journal:  Toxins (Basel)       Date:  2015-03-16       Impact factor: 4.546

7.  Report on the first detection of pectenotoxin-2, spirolide-a and their derivatives in French shellfish.

Authors:  Zouher Amzil; Manoella Sibat; Florence Royer; Nadine Masson; Eric Abadie
Journal:  Mar Drugs       Date:  2007-11-23       Impact factor: 5.118

Review 8.  Potential Threats Posed by New or Emerging Marine Biotoxins in UK Waters and Examination of Detection Methodologies Used for Their Control: Cyclic Imines.

Authors:  Keith Davidson; Clothilde Baker; Cowan Higgins; Wendy Higman; Sarah Swan; Andrea Veszelovszki; Andrew D Turner
Journal:  Mar Drugs       Date:  2015-11-26       Impact factor: 5.118

9.  New invertebrate vectors for PST, spirolides and okadaic acid in the North Atlantic.

Authors:  Marisa Silva; Aldo Barreiro; Paula Rodriguez; Paz Otero; Joana Azevedo; Amparo Alfonso; Luis M Botana; Vitor Vasconcelos
Journal:  Mar Drugs       Date:  2013-06-05       Impact factor: 5.118

10.  Confirmation of pinnatoxins and spirolides in shellfish and passive samplers from Catalonia (Spain) by liquid chromatography coupled with triple quadrupole and high-resolution hybrid tandem mass spectrometry.

Authors:  María García-Altares; Alexis Casanova; Vaishali Bane; Jorge Diogène; Ambrose Furey; Pablo de la Iglesia
Journal:  Mar Drugs       Date:  2014-06-23       Impact factor: 5.118

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