Literature DB >> 16564002

LRP6 holds the key to the entry of anthrax toxin.

James G Bann1, Lynette Cegelski, Scott J Hultgren.   

Abstract

In this issue of Cell, it is demonstrated that the low-density lipoprotein receptor-related protein 6 (LRP6) promotes endocytosis of the anthrax toxin into cells. LRP6 acts as a coreceptor with either TEM8 or CMG2, the two previously identified receptors for anthrax toxin.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16564002     DOI: 10.1016/j.cell.2006.03.007

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  1 in total

Review 1.  Designing inhibitors of anthrax toxin.

Authors:  Ekaterina M Nestorovich; Sergey M Bezrukov
Journal:  Expert Opin Drug Discov       Date:  2014-01-22       Impact factor: 6.098

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.