| Literature DB >> 16564000 |
Michael F Clarke1, Margaret Fuller.
Abstract
Recent evidence suggests that a subset of cancer cells within some tumors, the so-called cancer stem cells, may drive the growth and metastasis of these tumors. Understanding the pathways that regulate proliferation, self-renewal, survival, and differentiation of malignant and normal stem cells may shed light on mechanisms that lead to cancer and suggest better modes of treatment.Entities:
Mesh：
Year: 2006 PMID： 16564000 DOI： 10.1016/j.cell.2006.03.011
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582