| Literature DB >> 16563660 |
M F C Matos1, L I S P Leite, D Brustolim, J M de Siqueira, C A Carollo, A R Hellmann, N F G Pereira, D B da Silva.
Abstract
The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower than 25 microg/ml, a feature that was considered as revealing significant activity. Polycarpol showed borderline cytotoxicity, whereas the other compounds were inactive.Entities:
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Year: 2006 PMID： 16563660 DOI： 10.1016/j.fitote.2006.01.013
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882