Literature DB >> 1656333

Multicatalytic proteinase is present in Lewy bodies and neurofibrillary tangles in diffuse Lewy body disease brains.

S Kwak1, T Masaki, S Ishiura, H Sugita.   

Abstract

A non-lysosomal multicatalytic proteinase (MCP) is immunohistochemically visualized in Lewy bodies and loosely arranged globose tangles but not in the majority of compact neurofibrillary tangles in brains with cortical diffuse Lewy body disease. Virtually all Lewy bodies are immunoreactive to MCP, exhibiting various staining patterns where they are moderately diffuse, intense in the central core or intense in the peripheral rim. MCP may be involved in the formation of these inclusions.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1656333     DOI： 10.1016/0304-3940(91)90751-e

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  11 in total

Review 1.  The Lewy body in Parkinson's disease and related neurodegenerative disorders.

Authors:  Koichi Wakabayashi; Kunikazu Tanji; Saori Odagiri; Yasuo Miki; Fumiaki Mori; Hitoshi Takahashi
Journal:  Mol Neurobiol       Date:  2012-05-24       Impact factor: 5.590

Review 2.  Protein degradation pathways in Parkinson's disease: curse or blessing.

Authors:  Darius Ebrahimi-Fakhari; Lara Wahlster; Pamela J McLean
Journal:  Acta Neuropathol       Date:  2012-06-29       Impact factor: 17.088

3.  Immunohistochemical distribution and electron microscopic subcellular localization of the proteasome in the rat CNS.

Authors:  E Mengual; P Arizti; J Rodrigo; J M Giménez-Amaya; J G Castaño
Journal:  J Neurosci       Date:  1996-10-15       Impact factor: 6.167

4.  Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease.

Authors:  T Iwatsubo; H Yamaguchi; M Fujimuro; H Yokosawa; Y Ihara; J Q Trojanowski; V M Lee
Journal:  Am J Pathol       Date:  1996-05       Impact factor: 4.307

5.  Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity.

Authors:  Etsuo Susaki; Chie Kaneko-Oshikawa; Keishi Miyata; Mitsuhisa Tabata; Tetsuya Yamada; Yuichi Oike; Hideki Katagiri; Keiichi I Nakayama
Journal:  J Biol Chem       Date:  2010-02-26       Impact factor: 5.157

6.  The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.

Authors:  Jing L Guo; Arjan Buist; Alberto Soares; Kathleen Callaerts; Sara Calafate; Frederik Stevenaert; Joshua P Daniels; Bryan E Zoll; Alex Crowe; Kurt R Brunden; Diederik Moechars; Virginia M Y Lee
Journal:  J Biol Chem       Date:  2016-04-18       Impact factor: 5.157

7.  Susceptibility of myelin proteins to a neutral endoproteinase: the degradation of myelin basic protein (MBP) and P2 protein by purified bovine brain multicatalytic proteinase complex (MPC).

Authors:  J Lucas; D Lobo; E Terry; E L Hogan; N L Banik
Journal:  Neurochem Res       Date:  1992-12       Impact factor: 3.996

8.  Immunoreactivity profile of hippocampal CA2/3 neurites in diffuse Lewy body disease.

Authors:  D W Dickson; M L Schmidt; V M Lee; M L Zhao; S H Yen; J Q Trojanowski
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

9.  Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.

Authors:  Lisa M Sharkey; Nathaniel Safren; Amit S Pithadia; Julia E Gerson; Mark Dulchavsky; Svetlana Fischer; Ronak Patel; Gabrielle Lantis; Naila Ashraf; John H Kim; Alia Meliki; Eiko N Minakawa; Sami J Barmada; Magdalena I Ivanova; Henry L Paulson
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-17       Impact factor: 11.205

Review 10.  Neuronal death in Alzheimer's disease and therapeutic opportunities.

Authors:  Rossen Donev; Martin Kolev; Bruno Millet; Johannes Thome
Journal:  J Cell Mol Med       Date:  2009-09-01       Impact factor: 5.310
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.