Literature DB >> 16562896

Solvent-controlled asymmetric Strecker reaction: stereoselective synthesis of alpha-trifluoromethylated alpha-amino acids.

Hua Wang1, Xiaoming Zhao, Youhua Li, Long Lu.   

Abstract

[reaction: see text] Stereoselective approaches to alpha-trifluoromethylated alpha-amino acids (alpha-Tfm AAs) have been developed. The stereoconfigurations of the resulting alpha-Tfm AA precursors were well controlled by using different solvents. The optically active (S)-2-amino-2-phenyl-1,1,1-trifluoropropanoic acid was synthesized by this method.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16562896     DOI： 10.1021/ol0601186

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling.

Authors:  Shengyang Ni; Alberto F Garrido-Castro; Rohan R Merchant; Justine N de Gruyter; Daniel C Schmitt; James J Mousseau; Gary M Gallego; Shouliang Yang; Michael R Collins; Jennifer X Qiao; Kap-Sun Yeung; David R Langley; Michael A Poss; Paul M Scola; Tian Qin; Phil S Baran
Journal:  Angew Chem Int Ed Engl       Date:  2018-10-15       Impact factor: 15.336

2.  Strategies for the Catalytic Enantioselective Synthesis of α-Trifluoromethyl Amines.

Authors:  Chibueze I Onyeagusi; Steven J Malcolmson
Journal:  ACS Catal       Date:  2020-10-12       Impact factor: 13.084

3.  The [3+2] Annulation of CF3-Ketimines by Re Catalysis: Access to CF3-Containing Amino Heterocycles and Polyamides.

Authors:  Saisai Zhang; Xun-Yong Liu; Zhenbang Chang; Xinxin Qiao; Heng-Ying Xiong; Guangwu Zhang
Journal:  iScience       Date:  2020-10-20
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.