Literature DB >> 16562830

Cytotoxic xenia diterpenoids from the soft coral Xenia umbellata.

Ali A H El-Gamal1, Shang-Kwei Wang, Chang-Yih Duh.   

Abstract

Eleven new xenia diterpenoids, umbellacins A-G (1-7), 14,15-epoxy-xeniolide H (8), 3-acetyl-14,15-epoxy-xeniolide H (9), and umbellacins H and I (10, 11), were isolated from a methylene chloride-soluble fraction of the soft coral Xenia umbellata. The structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

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Year:  2006        PMID： 16562830     DOI： 10.1021/np058093r

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

1.  Induction of apoptosis by diterpenes from the soft coral Xenia elongata.

Authors:  Eric H Andrianasolo; Liti Haramaty; Kurt Degenhardt; Robin Mathew; Eileen White; Richard Lutz; Paul Falkowski
Journal:  J Nat Prod       Date:  2007-09-28       Impact factor: 4.050

2.  Concise Synthesis of the Xenibellols Core.

Authors:  Woo Han Kim; Angie R Angeles; Jun Hee Lee; Samuel J Danishefsky
Journal:  Tetrahedron Lett       Date:  2009-11-25       Impact factor: 2.415

3.  Studies for the synthesis of xenicane diterpenes. A stereocontrolled total synthesis of 4-hydroxydictyolactone.

Authors:  David R Williams; Martin J Walsh; Nathan A Miller
Journal:  J Am Chem Soc       Date:  2009-07-01       Impact factor: 15.419

4.  Targeted Isolation of Xenicane Diterpenoids from Taiwanese Soft Coral Asterospicularia laurae.

Authors:  Yu-Chi Lin; Yi-Jen Chen; Shu-Rong Chen; Wan-Ju Lien; Hsueh-Wei Chang; Yu-Liang Yang; Chia-Ching Liaw; Jui-Hsin Su; Ching-Yeu Chen; Yuan-Bin Cheng
Journal:  Mar Drugs       Date:  2021-02-25       Impact factor: 5.118

Review 5.  Cytotoxic and cytolytic cnidarian venoms. A review on health implications and possible therapeutic applications.

Authors:  Gian Luigi Mariottini; Luigi Pane
Journal:  Toxins (Basel)       Date:  2013-12-27       Impact factor: 4.546

Review 6.  Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms.

Authors:  Tatjana Huber; Lara Weisheit; Thomas Magauer
Journal:  Beilstein J Org Chem       Date:  2015-12-10       Impact factor: 2.883

Review 7.  Terpenoids from Marine Soft Coral of the Genus Xenia in 1977 to 2019.

Authors:  Shean-Yeaw Ng; Chin-Soon Phan; Takahiro Ishii; Takashi Kamada; Toshiyuki Hamada; Charles Santhanaraju Vairappan
Journal:  Molecules       Date:  2020-11-18       Impact factor: 4.411
  7 in total

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