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Literature DB >> 1656277

Activation of BPV-1 replication in vitro by the transcription factor E2.

L Yang¹, R Li, I J Mohr, R Clark, M R Botchan.

Abstract

Soluble extracts from uninfected murine cells supplemented with purified viral E1 and E2 proteins support the replication of exogenously added papilloma virus DNA. The E2 transactivator stimulates the binding of the E1 replication protein to the minimal origin of replication and activates DNA replication. These results support the concept that transcription factors have a direct role in the initiation of DNA replication in eukaryotes by participating in the assembly of a complex at the origin of replication.

Entities: Disease Species

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Year: 1991 PMID： 1656277 DOI： 10.1038/353628a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

148 in total

1. The E1 initiator recognizes multiple overlapping sites in the papillomavirus origin of DNA replication.

Authors: G Chen; A Stenlund
Journal: J Virol Date: 2001-01 Impact factor: 5.103

2. Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.

Authors: Eric J Enemark; Arne Stenlund; Leemor Joshua-Tor
Journal: EMBO J Date: 2002-03-15 Impact factor: 11.598

3. Sequential and ordered assembly of E1 initiator complexes on the papillomavirus origin of DNA replication generates progressive structural changes related to melting.

Authors: Grace Chen; Arne Stenlund
Journal: Mol Cell Biol Date: 2002-11 Impact factor: 4.272

4. Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.

Authors: T Yasugi; M Vidal; H Sakai; P M Howley; J D Benson
Journal: J Virol Date: 1997-08 Impact factor: 5.103

10. Binding of the human papillomavirus E1 origin-recognition protein is regulated through complex formation with the E2 enhancer-binding protein.

Authors: M G Frattini; L A Laimins
Journal: Proc Natl Acad Sci U S A Date: 1994-12-20 Impact factor: 11.205

Activation of BPV-1 replication in vitro by the transcription factor E2.

1. The E1 initiator recognizes multiple overlapping sites in the papillomavirus origin of DNA replication.

2. Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.

3. Sequential and ordered assembly of E1 initiator complexes on the papillomavirus origin of DNA replication generates progressive structural changes related to melting.

4. Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.

Review 5. Eukaryotic DNA helicases: essential enzymes for DNA transactions.

6. The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2.

7. POU domain transcription factors from different subclasses stimulate adenovirus DNA replication.

8. E1 protein of human papillomavirus is a DNA helicase/ATPase.

9. Long-term effect of interferon on keratinocytes that maintain human papillomavirus type 31.

10. Binding of the human papillomavirus E1 origin-recognition protein is regulated through complex formation with the E2 enhancer-binding protein.