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Literature DB >> 16562107

Mechanism of Action of Nalidixic Acid on Escherichia coli V. Possible Mutagenic Effect.

Abstract

Cook, Thomas M., (Sterling-Winthrop Research Institute, Rensselaer, N.Y.), William A. Goss, and William H. Deitz. Mechanism of action of nalidixic acid on Escherichia coli. V. Possible mutagenic effect. J. Bacteriol. 91:780-783. 1966.-With a streptomycin-dependent organism, Escherichia coli ATCC 11143, it has been shown that exposure to nalidixic acid, under conditions permitting some bactericidal action, results in an increased number of streptomycin-independent bacteria among the survivors. This effect is evident only with proliferating cultures, and is related to the concentration of nalidixic acid and the duration of exposure.

Entities: Chemical Species

Year: 1966 PMID： 16562107 PMCID： PMC314929 DOI： 10.1128/jb.91.2.780-783.1966

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

5 in total

1. A Method for Detection of Mutations, Using Streptomycin Dependence in Escherichia Coli.

Authors: G Bertani
Journal: Genetics Date: 1951-11 Impact factor: 4.562

2. Mutants of Escherichia coli requiring methionine or vitamin B12.

Authors: B D DAVIS; E S MINGIOLI
Journal: J Bacteriol Date: 1950-07 Impact factor: 3.490

3. Mechanism of action of nalidixic acid on Escherichia coli. IV. Effects on the stability of cellular constituents.

Authors: T M Cook; W H Deitz; W A Goss
Journal: J Bacteriol Date: 1966-02 Impact factor: 3.490

4. MECHANISM OF ACTION OF NALIDIXIC ACID ON ESCHERICHIA COLI.II. INHIBITION OF DEOXYRIBONUCLEIC ACID SYNTHESIS.

Authors: W A GOSS; W H DEITZ; T M COOK
Journal: J Bacteriol Date: 1965-04 Impact factor: 3.490

5. MECHANISM OF ACTION OF NALIDIXIC ACID ON ESCHERICHIA COLI.

Authors: W A GOSS; W H DEITZ; T M COOK
Journal: J Bacteriol Date: 1964-10 Impact factor: 3.490

5 in total

13 in total

1. Nalidixic acid for enrichment of auxotrophs in cultures of Salmonella typhimurium.

Authors: R M Weiner; M J Voll; T M Cook
Journal: Appl Microbiol Date: 1974-10

2. The action of inhibitors of nucleic acids synthesis on Euglena.

Authors: L Ebringer
Journal: Experientia Date: 1971-05-15

3. Delayed hypersensitivity to Staphylococcus aureus in mice: in vivo responses to isolated Staphylococcal antigens.

Authors: J B Bolen; J L Tribble
Journal: Immunology Date: 1979-12 Impact factor: 7.397

4. Effect of putative deoxyribonucleic acid inhibitors on macromolecular synthesis in Saccharomyces cerevisiae.

Authors: C T Wehr; R D Kudrna; L W Parks
Journal: J Bacteriol Date: 1970-06 Impact factor: 3.490

5. Ciprofloxacin-induced, low-level resistance to structurally unrelated antibiotics in Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus.

Authors: J Fung-Tomc; B Kolek; D P Bonner
Journal: Antimicrob Agents Chemother Date: 1993-06 Impact factor: 5.191

Mechanism of Action of Nalidixic Acid on Escherichia coli V. Possible Mutagenic Effect.

1. A Method for Detection of Mutations, Using Streptomycin Dependence in Escherichia Coli.

2. Mutants of Escherichia coli requiring methionine or vitamin B12.

3. Mechanism of action of nalidixic acid on Escherichia coli. IV. Effects on the stability of cellular constituents.

4. MECHANISM OF ACTION OF NALIDIXIC ACID ON ESCHERICHIA COLI.II. INHIBITION OF DEOXYRIBONUCLEIC ACID SYNTHESIS.

5. MECHANISM OF ACTION OF NALIDIXIC ACID ON ESCHERICHIA COLI.

1. Nalidixic acid for enrichment of auxotrophs in cultures of Salmonella typhimurium.

2. The action of inhibitors of nucleic acids synthesis on Euglena.

3. Delayed hypersensitivity to Staphylococcus aureus in mice: in vivo responses to isolated Staphylococcal antigens.

4. Effect of putative deoxyribonucleic acid inhibitors on macromolecular synthesis in Saccharomyces cerevisiae.

5. Ciprofloxacin-induced, low-level resistance to structurally unrelated antibiotics in Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus.

6. New hemolysin (gamma) produced by Escherichia coli.

7. Mechanism of action of nalidixic acid on Escherichia coli. Vi. Cell-free studies.

8. Activity of quinolones in the Ames Salmonella TA102 mutagenicity test and other bacterial genotoxicity assays.

9. Use of nalidixic acid for constructing the replication map of the Mycobacterium phlei chromosome.

10. Nalidixic Acid and the Metabolism of Escherichia coli.