Gene-Controlled Resistance to Acriflavine and Other Basic Dyes in Escherichia coli.

Nakamura, Hakobu (Konan University, Kobe, Japan). Gene-controlled resistance to acriflavine and other basic dyes in Escherichia coli. J. Bacteriol. 90:8-14. 1965.-The genetic determinant controlling the sensitivity of Escherichia coli K-12 W1895 to the basic dyes acriflavine, methylene blue, toluidine blue, crystal violet, methyl green, and pyronine B appears, from results of mating experiments, to be located between the marker governing the utilization of lactose and the origin of genetic transfer. The determinant controlling this resistance to basic dyes does not control resistance to acid dyes. After the introduction of the resistance gene into merozygotes, acriflavine resistance is not established immediately but develops slowly.