Literature DB >> 1655970

Hepatitis C virus: buoyant density of the factor VIII-derived isolate in sucrose.

D Bradley1, K McCaustland, K Krawczynski, J Spelbring, C Humphrey, E H Cook.   

Abstract

Physicochemical and molecular characterization studies of hepatitis C virus (HCV), the major causative agent of parenterally transmitted non-A, non-B hepatitis (PT-NANBH), strongly suggest that it is a pesti-/flavivirus-like virus. Additional studies show that the buoyant density of plasma-derived HCV in sucrose is significantly lower than that of most tissue culture-derived flaviviruses (1.20 g/cm3). Our finding suggests, but does not prove, that at least one physicochemical property of HCV is more similar to that of the pestiviruses, bovine viral diarrhea virus (BVDV) and hog cholera virus (HogCV), than that of the flaviviruses.

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Year:  1991        PMID： 1655970     DOI： 10.1002/jmv.1890340315

Source DB:  PubMed          Journal:  J Med Virol        ISSN： 0146-6615            Impact factor:   2.327


  51 in total

1.  Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor.

Authors:  S Wünschmann; J D Medh; D Klinzmann; W N Schmidt; J T Stapleton
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

2.  Generation of hepatitis C virus-like particles by use of a recombinant vesicular stomatitis virus vector.

Authors:  Heather J Ezelle; Dubravka Markovic; Glen N Barber
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

3.  Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture.

Authors:  Pablo Gastaminza; Kelly A Dryden; Bryan Boyd; Malcolm R Wood; Mansun Law; Mark Yeager; Francis V Chisari
Journal:  J Virol       Date:  2010-08-04       Impact factor: 5.103

4.  Ultracentrifugation of serum samples allows detection of hepatitis C virus RNA in patients with occult hepatitis C.

Authors:  Javier Bartolomé; Juan Manuel López-Alcorocho; Inmaculada Castillo; Elena Rodríguez-Iñigo; Juan Antonio Quiroga; Ricardo Palacios; Vicente Carreño
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

5.  A novel small molecule inhibitor of hepatitis C virus entry.

Authors:  Carl J Baldick; Michael J Wichroski; Annapurna Pendri; Ann W Walsh; Jie Fang; Charles E Mazzucco; Kevin A Pokornowski; Ronald E Rose; Betsy J Eggers; Mayla Hsu; Weixu Zhai; Guangzhi Zhai; Samuel W Gerritz; Michael A Poss; Nicholas A Meanwell; Mark I Cockett; Daniel J Tenney
Journal:  PLoS Pathog       Date:  2010-09-02       Impact factor: 6.823

6.  Association of hepatitis C virus in human sera with beta-lipoprotein.

Authors:  R Thomssen; S Bonk; C Propfe; K H Heermann; H G Köchel; A Uy
Journal:  Med Microbiol Immunol       Date:  1992       Impact factor: 3.402

7.  Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses.

Authors:  J Dubuisson; H H Hsu; R C Cheung; H B Greenberg; D G Russell; C M Rice
Journal:  J Virol       Date:  1994-10       Impact factor: 5.103

8.  Entry of hepatitis C virus into the cell: a therapeutic target.

Authors:  José Antonio Del Campo; Ángela Rojas; Manuel Romero-Gómez
Journal:  World J Gastroenterol       Date:  2012-09-07       Impact factor: 5.742

9.  Characterization of long-term cultures of hepatitis C virus.

Authors:  N Nakajima; M Hijikata; H Yoshikura; Y K Shimizu
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

10.  Secretion of hepatitis C virus envelope glycoproteins depends on assembly of apolipoprotein B positive lipoproteins.

Authors:  Vinca Icard; Olivier Diaz; Caroline Scholtes; Laure Perrin-Cocon; Christophe Ramière; Ralf Bartenschlager; Francois Penin; Vincent Lotteau; Patrice André
Journal:  PLoS One       Date:  2009-01-21       Impact factor: 3.240
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