Literature DB >> 1655932

Arachidonic acid metabolism in human and bovine retina.

P S Kulkarni1.   

Abstract

Arachidonic acid (AA) metabolism in the human and bovine retina was assessed. This study demonstrates that the human and bovine retina can synthesize prostaglandin (PG) E2, F2 alpha, I2, D2 and thromboxane A2 from 14C-AA. This tissue also synthesized leukotriene (LT) B4 and 12-hydroxyeicosatetraenoic acid (12-HETE). Although human and bovine retina metabolized AA into PGs and LTs, the ability to synthesize these products was considerably less than some other ocular tissues of various species.

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Year:  1991        PMID: 1655932     DOI: 10.1089/jop.1991.7.135

Source DB:  PubMed          Journal:  J Ocul Pharmacol        ISSN: 8756-3320


  3 in total

1.  Expression of phospholipases A2 and C in human corneal epithelial cells.

Authors:  Solange Landreville; Stéphanie Coulombe; Patrick Carrier; Michael H Gelb; Sylvain L Guérin; Christian Salesse
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-11       Impact factor: 4.799

2.  Light-evoked arachidonic acid release in the retina: illuminance/duration dependence and the effects of quinacrine, mellitin and lithium. Light-evoked arachidonic acid release.

Authors:  H Jung; C Remé
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1994-03       Impact factor: 3.117

3.  Expression of thromboxane synthase and the thromboxane-prostanoid receptor in the mouse and rat retina.

Authors:  William S Wright; Robert M McElhatten; Norman R Harris
Journal:  Exp Eye Res       Date:  2009-06-11       Impact factor: 3.467

  3 in total

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