Literature DB >> 16558092

Persistent infection of mice with the virus of lymphocytic choriomeningitis: virus-specific immunological tolerance.

J Cihak1, F Lehmann-Grube.   

Abstract

Lymphocytic choriomeningitis (LCM) virus-infected culture cells as targets were markedly reduced in numbers when incubated in vitro with spleen cells from LCM virus-immune mice, even if the cells were taken months after a subcutaneous immunizing infection of the donor animal. Spleen cells from mice persistently infected with LCM virus had no effect on target cells. Also, mitomycin C-blocked LCM virus-infected culture cells stimulated the incorporation of radiolabeled thymidine into spleen cells from LCM virus-immune mice. No stimulation was observed with spleen cells from LCM virus carrier mice. It was concluded that cell-mediated immunity directed against LCM virion surface antigen(s) is absent in LCM virus carrier mice.

Entities:  

Year:  1974        PMID： 16558092      PMCID： PMC423064          DOI： 10.1128/iai.10.5.1072-1076.1974

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  13 in total

1.  LYMPHOCYTIC CHORIOMENINGITIS IN THE MOUSE. II. ESTABLISHMENT OF CARRIER COLONIES.

Authors:  F LEHMANN-GRUBE
Journal:  Arch Gesamte Virusforsch       Date:  1964

2.  Requirements for growth of single human cells.

Authors:  R Z LOCKART; H EAGLE
Journal:  Science       Date:  1959-01-30       Impact factor: 47.728

3.  Specificity and development of cytotoxic thymus-derived lymphocytes in lymphocytic choriomeningitis.

Authors:  P C Doherty; R M Zinkernagel; I A Ramshaw
Journal:  J Immunol       Date:  1974-04       Impact factor: 5.422

Review 4.  Persistent infection of the mouse with the virus of lymphocytic choriomeningitis.

Authors:  F Lehmann-Grube
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1972

5.  Further evidence for autonomy of T cells mediating specific in vitro cytotoxicity: efficiency of very small amounts of highly purified T cells.

Authors:  P Golstein; H Blomgren
Journal:  Cell Immunol       Date:  1973-10       Impact factor: 4.868

6.  A new method for the titration of lymphocytic choriomeningitis viruses.

Authors:  F Lehmann-Grube; R Hesse
Journal:  Arch Gesamte Virusforsch       Date:  1967

7.  Interaction between antigenically different cells. Virus-induced cytotoxicity by immune lymphoid cells in vitro.

Authors:  C Lundstedt
Journal:  Acta Pathol Microbiol Scand       Date:  1969

8.  Mouse thymic iso-antigens.

Authors:  A E Reif; J M Allen
Journal:  Nature       Date:  1966-01-29       Impact factor: 49.962

9.  Studies on cell-mediated immunity to lymphocytic choriomeningitis virus in mice.

Authors:  O Marker; M Volkert
Journal:  J Exp Med       Date:  1973-06-01       Impact factor: 14.307

10.  Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. I. Relationship of antibody production to disease in neonatally infected mice.

Authors:  M B Oldstone; F J Dixon
Journal:  J Exp Med       Date:  1969-03-01       Impact factor: 14.307
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  10 in total

1.  The activity of T and B lymphocytes in immunity and tolerance to the lymphocytic choriomeningitis virus in mice.

Authors:  M Volkert; K Bro-Jorgensen; O Marker; B Rubin; L Trier
Journal:  Immunology       Date:  1975-09       Impact factor: 7.397

2.  LCM virus infection of cells in vitro.

Authors:  F Lehmann-Grube; M Popescu; H Schaefer; H H Gschwender
Journal:  Bull World Health Organ       Date:  1975       Impact factor: 9.408

3.  Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure.

Authors:  B Odermatt; M Eppler; T P Leist; H Hengartner; R M Zinkernagel
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-15       Impact factor: 11.205

4.  Immunological tolerance to lymphocytic choriomeningitis virus in neonatally infected virus carrier mice: evidence supporting a clonal inactivation mechanism.

Authors:  J Cihak; F Lehmann-Grube
Journal:  Immunology       Date:  1978-02       Impact factor: 7.397

5.  Lymphocytic choriomeningitis virus. II. Characterization of extractable complement-fixing activity.

Authors:  H H Geschwender; G Rutter; F Lehmann-Grube
Journal:  Med Microbiol Immunol       Date:  1976-06-01       Impact factor: 3.402

6.  Characterization of a nonvirulent variant of lymphocytic choriomeningitis virus.

Authors:  P R Brayton; H F Maassab
Journal:  Arch Virol       Date:  1982       Impact factor: 2.574

7.  Persistent LCM virus infection in the mouse. Immunity and tolerance.

Authors:  M Volkert; K Bro-Jorgensen; O Marker
Journal:  Bull World Health Organ       Date:  1975       Impact factor: 9.408

8.  Lymphocytic choriomeningitis virus infection in fetal, newborn, and young adult Syrian hamsters (Mesocricetus auratus).

Authors:  J C Parker; H J Igel; R K Reynolds; A M Lewis; W P Rowe
Journal:  Infect Immun       Date:  1976-03       Impact factor: 3.441

9.  Mechanisms of suppression of cytotoxic T-cell responses in murine lymphocytic choriomeningitis virus infection.

Authors:  M B Dunlop; R V Blanden
Journal:  J Exp Med       Date:  1977-05-01       Impact factor: 14.307

10.  Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses.

Authors:  Nadine Honke; Namir Shaabani; Katja Merches; Asmae Gassa; Anke Kraft; Katrin Ehrhardt; Dieter Häussinger; Max Löhning; Ulf Dittmer; Hartmut Hengel; Mike Recher; Philipp A Lang; Karl S Lang
Journal:  Eur J Immunol       Date:  2015-11-17       Impact factor: 5.532
  10 in total

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