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Literature DB >> 16558029

Characteristics of cytophilic antibody in the mouse.

Abstract

Immunoglobulin M hemagglutinin and antibody cytophilic for macrophages were produced simultaneously in mice after primary antigenic stimulation with sheep erythrocytes in saline. Antigen emulsified in Freund's complete adjuvant induced formation of cytophilic antibody (CA) in high titer. Purified cytophilic globulin was isolated by permitting it to attach to macrophages in vitro and eluting it at 56 C. The chromatographic elution pattern, molecular weight, and resistance to mercaptoethanol suggested that CA is a member of the immunoglobulin G class of immunoglobulins.

Entities: Chemical Species

Year: 1971 PMID： 16558029 PMCID： PMC416209 DOI： 10.1128/iai.3.5.637-641.1971

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

11 in total

2. Cytophilic antibodies in mice contact-sensitized with oxazolone. Immunochemical characterization and preferential binding to a trypsin-sensitive macrophage receptor.

Authors: P W Askenase; B J Hayden
Journal: Immunology Date: 1974-10 Impact factor: 7.397

Review 3. Macrophage-cytophilic antibodies and the functions of macrophage-bound immunoglobulins.

Authors: I R Tizard
Journal: Bacteriol Rev Date: 1971-12

3 in total

Characteristics of cytophilic antibody in the mouse.

1. CYTOPHILIC ANTIBODY IN GUINEA-PIGS WITH DELAYED-TYPE HYPERSENSITIVITY.

2. THE BASIS FOR IMMUNITY TO MOUSE TYPHOID. 3. CELL-BOUND ANTIBODY.

3. The adsorption of antigen by spleen cells previously treated with antiserum in vitro.

Review 4. Macrophage cytophilic antibodies and delayed hypersensitivity.

5. Sedimentation properties of antibody cytophilic for macrophages.

6. Properties of antibodies cytophilic for macrophages.

7. Passive sensitization of tissue cells. 3. A primate macrophage-cytophilic antibody.

8. Experimental delayed type allergy without demonstrable antibodies. I. Absence of cytophilic antibodies.

9. Characterization of a small proteolytic enzyme which lyses bacterial cell walls.

10. Cytophilic antibody. I. Nature of the macrophage receptor.

1. Immune competence of hereditarily asplenic mice.

2. Cytophilic antibodies in mice contact-sensitized with oxazolone. Immunochemical characterization and preferential binding to a trypsin-sensitive macrophage receptor.

Review 3. Macrophage-cytophilic antibodies and the functions of macrophage-bound immunoglobulins.