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Literature DB >> 16557968

Pathogenicity and Antigenicity of Clones from Strains of Marek's Disease Virus and the Herpesvirus of Turkeys.

H G Purchase¹, B R Burmester, C H Cunningham.

Abstract

Virus was extracted by filtration from chicken embryo fibroblast cultures infected with the JM, high passage JM(JMHP), GA, and RPL39 strains of Marek's disease virus (MDV) and from the herpesvirus of turkeys (HVT) and purified by cloning. The plaques produced by clones of HVT, JMHP, and other MDV strains differed in morphology from one another. Clones of MDV varied greatly in pathogenicity for chickens, but JMHP and HVT were nonpathogenic. Two pathogenic clones of JM virus and a clone of JMHP virus lacked the A precipitin antigen present in all other clones tested. All clones had at least one B antigen in common. HVT and MDV clones with and without the A precipitin antigen could be distinguished from each other by the indirect fluorescent antibody test. Changes in virus-host cell relationships, loss of pathogenicity, and loss of the A antigens were independent events.

Entities: Gene Species

Year: 1971 PMID： 16557968 PMCID： PMC416146 DOI： 10.1128/iai.3.2.295-303.1971

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

24 in total

1. PATHOLOGICAL CHANGES INDUCED BY HERPES SIMPLEX VIRUS IN THE CHORIOALLANTOIC MEMBRANES OF HATCHING EGGS.

Authors: S NU; J KAMAHORA
Journal: Biken J Date: 1963-10

2. ABORTIVE INFECTION OF CANINE CELLS BY HERPES SIMPLEX VIRUS. I. CHARACTERIZATION OF VIRAL PROGENY FROM CO-OPERATIVE INFECTION WITH MUTANTS DIFFERING IN CAPACITY TO MULTIPLY IN CANINE CELLS.

Authors: B ROIZMAN; L AURELIAN
Journal: J Mol Biol Date: 1965-03 Impact factor: 5.469

3. The isolation and properties of a variant of Herpes simplex producing multinucleated giant cells in monolayer cultures in the presence of antibody.

Authors: M D HOGGAN; B ROIZMAN
Journal: Am J Hyg Date: 1959-09

4. Cell culture techniques for primary isolation of Marek's disease-associated herpesvirus.

Authors: R L Witter; J J Solomon; G H Burgoyne
Journal: Avian Dis Date: 1969-02 Impact factor: 1.577

5. Virus-specific immunofluorescent and precipitin antigens and cell-free virus in the tissues of birds infected with Marek's disease.

Authors: H G Purchase
Journal: Cancer Res Date: 1970-06 Impact factor: 12.701

6. Relation of pock size on chorioallantoic membrane to antigenic type of herpesvirus hominis.

Authors: A J Nahmias; W R Dowdle; Z M Naib; A Highsmith; R W Harwell; W E Josey
Journal: Proc Soc Exp Biol Med Date: 1968-04

7. Characterization of five isolates of Marek's disease.

Authors: H G Purchase; P M Biggs
Journal: Res Vet Sci Date: 1967-10 Impact factor: 2.534

8. Agent of Marek's disease in tissue culture.

Authors: A E Churchill; P M Biggs
Journal: Nature Date: 1967-07-29 Impact factor: 49.962

9. Herpes-type virus isolated in cell culture from tumors of chickens with Marek's disease. I. Studies in cell culture.

Authors: A E Churchill
Journal: J Natl Cancer Inst Date: 1968-10 Impact factor: 13.506

10. Effect of different conditions on precipitation in agar between Marek's disease antigen and antibody.

Authors: W Okazaki; H G Purchase; L Noll
Journal: Avian Dis Date: 1970-08 Impact factor: 1.577

16 in total

1. Marek's Disease Herpesviruses I. Production and Preliminary Characterization of Marek's Disease Herpesvirus A Antigen.

Authors: P A Long; P Kaveh-Yamini; L F Velicer
Journal: J Virol Date: 1975-05 Impact factor: 5.103

2. Effect of in vitro adaptation of Marek's disease virus on pock induction on the chorioallantoic membrane of embryonated chicken eggs.

Authors: J M Sharma; B D Coulson; E Young
Journal: Infect Immun Date: 1976-01 Impact factor: 3.441

10. [Structure and function of virus-induced antigens in cultured cells infected with Merek's disease and turkey herpes viruses. II. Isolation of intracellular antigens from infected cells (author's transl)].

Authors: O R Kaaden
Journal: Med Microbiol Immunol Date: 1977-10-07 Impact factor: 3.402

Pathogenicity and Antigenicity of Clones from Strains of Marek's Disease Virus and the Herpesvirus of Turkeys.

1. PATHOLOGICAL CHANGES INDUCED BY HERPES SIMPLEX VIRUS IN THE CHORIOALLANTOIC MEMBRANES OF HATCHING EGGS.

2. ABORTIVE INFECTION OF CANINE CELLS BY HERPES SIMPLEX VIRUS. I. CHARACTERIZATION OF VIRAL PROGENY FROM CO-OPERATIVE INFECTION WITH MUTANTS DIFFERING IN CAPACITY TO MULTIPLY IN CANINE CELLS.

3. The isolation and properties of a variant of Herpes simplex producing multinucleated giant cells in monolayer cultures in the presence of antibody.

4. Cell culture techniques for primary isolation of Marek's disease-associated herpesvirus.

5. Virus-specific immunofluorescent and precipitin antigens and cell-free virus in the tissues of birds infected with Marek's disease.

6. Relation of pock size on chorioallantoic membrane to antigenic type of herpesvirus hominis.

7. Characterization of five isolates of Marek's disease.

8. Agent of Marek's disease in tissue culture.

9. Herpes-type virus isolated in cell culture from tumors of chickens with Marek's disease. I. Studies in cell culture.

10. Effect of different conditions on precipitation in agar between Marek's disease antigen and antibody.

1. Marek's Disease Herpesviruses I. Production and Preliminary Characterization of Marek's Disease Herpesvirus A Antigen.

2. Effect of in vitro adaptation of Marek's disease virus on pock induction on the chorioallantoic membrane of embryonated chicken eggs.

3. Demyelination in allergic and Marek's disease virus induced neuritis. Comparative electron microscopic studies.

4. Small-plaque variant of canine herpesvirus with reduced pathogenicity for newborn pups.

5. Marke's disease herpesviruses. III. Purification and characterization of Marek's disease herpesvirus B antigen.

6. Immunoferritin studies of Marek's disease virus directed intracellular and membrane antigens.

7. Induction of deoxyribonucleic acid synthesis and the oncogenicity of Marek's disease virus.

8. Genetic relatedness of virulent and avirulent strains of Marek's disease virus.

9. Pathogenesis of Marek's disease in old chickens: lesion regression as the basis for age-related resistance.

10. [Structure and function of virus-induced antigens in cultured cells infected with Merek's disease and turkey herpes viruses. II. Isolation of intracellular antigens from infected cells (author's transl)].