| Literature DB >> 16557961 |
Abstract
Mouse resistance to foot-and-mouth disease virus (FMDV) was induced by intraperitoneal injections of pyran copolymer. A biphasic pattern of protection occurred with greatest resistance 4 and 48 hr after injection of this polyanion. Viremia was not detectable in pretreated mice challenge-exposed with FMDV. Incubation of virus with pyran did not alter viral infectivity in mice or tissue culture. Serum interferon was demonstrated 1 and 2 days after pyran administration.Entities:
Year: 1971 PMID: 16557961 PMCID: PMC416139 DOI: 10.1128/iai.3.2.249-253.1971
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441