Literature DB >> 16557851

Physicochemical Properties of Neisseria meningitidis Group C and Y Polysaccharide Antigens.

M A Apicella1, J A Robinson.   

Abstract

Chemical and physical studies of the Neisseria meningitidis group C and Y antigens indicated that these preparations are acidic polysaccharides. The group C antigen contains predominately n-acetyl neuraminic acid, with small amounts of glucose, glucosamine, and mannose, whereas the group Y antigen contains glucose, glucosamine, and mannose. The molecular weights of the group C and Y antigens were found to be 88,000 and 197,000, respectively. The group C antigen was susceptible to neuraminidase digestion. Finally, the immunological reactivity of neither antigen was inhibited in hemagglutination or immunodiffusion systems by neutral or substituted sugars.

Entities:  

Year:  1970        PMID： 16557851      PMCID： PMC416022          DOI： 10.1128/iai.2.4.392-397.1970

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  19 in total

1.  The thiobarbituric acid assay of sialic acids.

Authors:  L WARREN
Journal:  J Biol Chem       Date:  1959-08       Impact factor: 5.157

2.  Studies on an endotoxin of a group C Neisseria meningitidis.

Authors:  S E MERGENHAGEN; G R MARTIN; E SCHIFFMANN
Journal:  J Immunol       Date:  1963-02       Impact factor: 5.422

3.  Spectrophotometric method for the determination of free pentose and pentose in nucleotides.

Authors:  Z DISCHE
Journal:  J Biol Chem       Date:  1949-11       Impact factor: 5.157

4.  Chromic chloride: a coupling reagent for passive hemagglutination reactions.

Authors:  E R Gold; H H Fudenberg
Journal:  J Immunol       Date:  1967-11       Impact factor: 5.422

5.  The sialic acids. VI. Purification and properties of sialidase from Clostridium perfringens.

Authors:  J T Cassidy; G W Jourdian; S Roseman
Journal:  J Biol Chem       Date:  1965-09       Impact factor: 5.157

6.  Acrylamide gel electrophoresis of acidic mucopolysaccharides.

Authors:  J C Hilborn; P A Anastassiadis
Journal:  Anal Biochem       Date:  1969-10-01       Impact factor: 3.365

Review 7.  Tumors and serum glycoproteins. The 'symbodies'.

Authors:  C A Apffel; J H Peters
Journal:  Prog Exp Tumor Res       Date:  1969

8.  Isolation and Characterization of Neisseria meningitidis Groups A, C, X, and Y Polysaccharide Antigens.

Authors:  J A Robinson; M A Apicella
Journal:  Infect Immun       Date:  1970-01       Impact factor: 3.441

9.  Immunochemistry of the cell walls of Listeria monocytogenes.

Authors:  W W Ullmann; J A Cameron
Journal:  J Bacteriol       Date:  1969-05       Impact factor: 3.490

10.  Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharides.

Authors:  E C Gotschlich; T Y Liu; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307
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  3 in total

Review 1.  The meningococcus and mechanisms of pathogenicity.

Authors:  I W DeVoe
Journal:  Microbiol Rev       Date:  1982-06

2.  Physicochemical properties of Neisseria meningitidis group X polysaccharide antigen.

Authors:  M A Apicella; J A Robinson
Journal:  Infect Immun       Date:  1972-11       Impact factor: 3.441

3.  Degradation of the polysaccharide component of gonococcal lipopolysaccharide by gonococcal and meningococcal sonic extracts.

Authors:  M A Apicella; J F Breen; N C Gagliardi
Journal:  Infect Immun       Date:  1978-04       Impact factor: 3.441
  3 in total

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