Literature DB >> 16557482

The effects of ginsenoside Re and its metabolite, ginsenoside Rh1, on 12-O-tetradecanoylphorbol 13-acetate- and oxazolone-induced mouse dermatitis models.

Yong-Wook Shin1, Eun-Ah Bae, Sung-Soo Kim, Young-Chul Lee, Boo-Young Lee, Dong-Hyun Kim.   

Abstract

The effects of the main constituent ginsenoside Re in ginseng and its metabolite, ginsenoside Rh1, were investigated in 12-O-tetradecanoylphorbol 13-acetate (TPA)- and oxazolone-induced mouse ear dermatitis models. Ginsenoside Rh1 potently suppressed the TPA- and oxazolone-induced swellings as well as mRNA expression levels of cyclooxygenase-2, IL-1beta and TNF-alpha, although these were only weakly inhibited by ginsenoside Re.

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Year:  2006        PMID： 16557482     DOI： 10.1055/s-2005-916217

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  4 in total

Review 1.  Chinese medicines reported to have effects on contact dermatitis in the last 20 years.

Authors:  Youngchul Jung; Byungju Kim; Mi Heon Ryu; Hyungwoo Kim
Journal:  Chin J Integr Med       Date:  2017-03-02       Impact factor: 1.978

2.  Protopanaxatriol Ginsenoside Rh1 Upregulates Phase II Antioxidant Enzyme Gene Expression in Rat Primary Astrocytes: Involvement of MAP Kinases and Nrf2/ARE Signaling.

Authors:  Ji-Sun Jung; Sang-Yoon Lee; Dong-Hyun Kim; Hee-Sun Kim
Journal:  Biomol Ther (Seoul)       Date:  2016-01-01       Impact factor: 4.634

3.  Ginsenoside Re Inhibits Osteoclast Differentiation in Mouse Bone Marrow-Derived Macrophages and Zebrafish Scale Model.

Authors:  Chan-Mi Park; Hye-Min Kim; Dong Hyun Kim; Ho-Jin Han; Haneul Noh; Jae-Hyuk Jang; Soo-Hyun Park; Han-Jung Chae; Soo-Wan Chae; Eun Kyoung Ryu; Sangku Lee; Kangdong Liu; Haidan Liu; Jong-Seog Ahn; Young Ock Kim; Bo-Yeon Kim; Nak-Kyun Soung
Journal:  Mol Cells       Date:  2016-12-06       Impact factor: 5.034

4.  Efficacy of korean red ginseng in the treatment of atopic dermatitis.

Authors:  Kyung Goo Lee; Sang Wook Son
Journal:  J Ginseng Res       Date:  2011-06       Impact factor: 6.060
  4 in total

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