Literature DB >> 16557410

[Stem cell therapy for the regeneration of heart muscle].

G Steinhoff1.   

Abstract

The loss of contractile heart tissue - often a sequelae of cardiac infarction - is caused by the limited regeneration capacity of the heart and usually leads to irreversible organ damage. Modification of this regeneration capacity by cell-based cardiac therapies with precursor and stem cells opens a new therapeutic field. A number of different (stem)cell types and applications are currently being evaluated. The possibilities and risks of the therapy are not easily foreseeable, however, clinical applications are already visible. In the light of stem cell research, the vision of regrowth of the heart in analogy to the Prometheus saga is obtaining a scientific explanation and may lead to new cardiac therapies.

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Year:  2006        PMID: 16557410     DOI: 10.1007/s00108-006-1610-2

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  28 in total

Review 1.  Regenerating the heart.

Authors:  Michael A Laflamme; Charles E Murry
Journal:  Nat Biotechnol       Date:  2005-07       Impact factor: 54.908

2.  Mobilization of endothelial progenitor cells in patients with acute myocardial infarction.

Authors:  S Shintani; T Murohara; H Ikeda; T Ueno; T Honma; A Katoh; K Sasaki; T Shimada; Y Oike; T Imaizumi
Journal:  Circulation       Date:  2001-06-12       Impact factor: 29.690

3.  Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure.

Authors:  Emerson C Perin; Hans F R Dohmann; Radovan Borojevic; Suzana A Silva; Andre L S Sousa; Claudio T Mesquita; Maria I D Rossi; Antonio C Carvalho; Helio S Dutra; Hans J F Dohmann; Guilherme V Silva; Luciano Belém; Ricardo Vivacqua; Fernando O D Rangel; Roberto Esporcatte; Yong J Geng; William K Vaughn; Joao A R Assad; Evandro T Mesquita; James T Willerson
Journal:  Circulation       Date:  2003-04-21       Impact factor: 29.690

4.  Mobilized bone marrow cells repair the infarcted heart, improving function and survival.

Authors:  D Orlic; J Kajstura; S Chimenti; F Limana; I Jakoniuk; F Quaini; B Nadal-Ginard; D M Bodine; A Leri; P Anversa
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-14       Impact factor: 11.205

5.  Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation.

Authors:  Noel M Caplice; T Jared Bunch; Paul G Stalboerger; Shaohua Wang; David Simper; Dylan V Miller; Stephen J Russell; Mark R Litzow; William D Edwards
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-28       Impact factor: 11.205

6.  Monitoring of bone marrow cell homing into the infarcted human myocardium.

Authors:  Michael Hofmann; Kai C Wollert; Gerd P Meyer; Alix Menke; Lubomir Arseniev; Bernd Hertenstein; Arnold Ganser; Wolfram H Knapp; Helmut Drexler
Journal:  Circulation       Date:  2005-04-25       Impact factor: 29.690

7.  Chimerism of the transplanted heart.

Authors:  Federico Quaini; Konrad Urbanek; Antonio P Beltrami; Nicoletta Finato; Carlo A Beltrami; Bernardo Nadal-Ginard; Jan Kajstura; Annarosa Leri; Piero Anversa
Journal:  N Engl J Med       Date:  2002-01-03       Impact factor: 91.245

8.  Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts.

Authors:  Michael A Laflamme; David Myerson; Jeffrey E Saffitz; Charles E Murry
Journal:  Circ Res       Date:  2002-04-05       Impact factor: 17.367

9.  Muscle regeneration by bone marrow-derived myogenic progenitors.

Authors:  G Ferrari; G Cusella-De Angelis; M Coletta; E Paolucci; A Stornaiuolo; G Cossu; F Mavilio
Journal:  Science       Date:  1998-03-06       Impact factor: 47.728

10.  Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts.

Authors:  Charles E Murry; Mark H Soonpaa; Hans Reinecke; Hidehiro Nakajima; Hisako O Nakajima; Michael Rubart; Kishore B S Pasumarthi; Jitka Ismail Virag; Stephen H Bartelmez; Veronica Poppa; Gillian Bradford; Joshua D Dowell; David A Williams; Loren J Field
Journal:  Nature       Date:  2004-03-21       Impact factor: 49.962

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