Literature DB >> 16556084

Genital herpes: antiviral therapy for symptom relief and prevention of transmission.

Rachna Gupta1, Anna Wald.   

Abstract

The episodic and daily suppressive treatment of genital herpes is safe and effective with the currently available antiviral agents: acyclovir, valacyclovir and famciclovir. Clinical strategies for the comprehensive management of genital herpes simplex virus infections are recommended. Data from recent clinical trials demonstrating the efficacy of shorter duration of therapy for recurrences and the use of antivirals for the prevention of transmission are reviewed in this article. The factors influencing the choice of therapy, such as cost, ease of dosing and acyclovir resistance are also discussed.

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Year:  2006        PMID： 16556084     DOI： 10.1517/14656566.7.6.665

Source DB:  PubMed          Journal:  Expert Opin Pharmacother        ISSN： 1465-6566            Impact factor:   3.889


  5 in total

1.  Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial.

Authors:  Jairam R Lingappa; Jared M Baeten; Anna Wald; James P Hughes; Katherine K Thomas; Andrew Mujugira; Nelly Mugo; Elizabeth A Bukusi; Craig R Cohen; Elly Katabira; Allan Ronald; James Kiarie; Carey Farquhar; Grace John Stewart; Joseph Makhema; Myron Essex; Edwin Were; Kenneth H Fife; Guy de Bruyn; Glenda E Gray; James A McIntyre; Rachel Manongi; Saidi Kapiga; David Coetzee; Susan Allen; Mubiana Inambao; Kayitesi Kayitenkore; Etienne Karita; William Kanweka; Sinead Delany; Helen Rees; Bellington Vwalika; Amalia S Magaret; Richard S Wang; Lara Kidoguchi; Linda Barnes; Renee Ridzon; Lawrence Corey; Connie Celum
Journal:  Lancet       Date:  2010-02-12       Impact factor: 79.321

Review 2.  Clinical and therapeutic issues for herpes simplex virus-2 and HIV co-infection.

Authors:  Jairam R Lingappa; Connie Celum
Journal:  Drugs       Date:  2007       Impact factor: 9.546

3.  A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation.

Authors:  S T Gammon; M Bernstein; D P Schuster; D Piwnica-Worms
Journal:  Anal Biochem       Date:  2007-06-15       Impact factor: 3.365

4.  Effectiveness and safety of oral acyclovir 1 g twice a day for 3 days in the management of genital herpes.

Authors:  Kaushal K Verma; Mahendra Sonune; Lalit Dar; Neetu Bhari; Banwari Lal Jangid
Journal:  Indian J Sex Transm Dis AIDS       Date:  2021-02-15

5.  Summary measures of adherence using pill counts in two HIV prevention trials: the need for standardisation in reporting.

Authors:  Kathy Baisley; Jared M Baeten; James P Hughes; Deborah J Donnell; Jing Wang; Richard Hayes; Deborah Watson Jones; Connie Celum
Journal:  AIDS Behav       Date:  2013-11
  5 in total

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