Literature DB >> 1655562

Clustering of hepatocellular carcinoma in Alaska Native families.

S R Alberts1, A P Lanier, B J McMahon, A Harpster, L R Bulkow, W L Heyward, C Murray.   

Abstract

Alaska Natives have a high incidence of hepatocellular carcinoma (HCC), with regional, ethnic, village, and familial clustering. During 1969-1988, 15 of the 45 incident cases of HCC in Alaska Natives occurred in 5 families. This report presents epidemiologic, virologic, and immunogenetic data on these 5 families. The results of hepatitis B virus (HBV) serologic testing indicates that HBV infection was an important factor in 4 of the 5 families. Human lymphocyte antigen (HLA) testing was performed in 3 families. The HLA results are reviewed in relationship to the familial clustering of HCC.

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Year:  1991        PMID: 1655562     DOI: 10.1002/gepi.1370080206

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN: 0741-0395            Impact factor:   2.135


  9 in total

1.  Epidemiology and carcinogenesis of hepatocellular carcinoma.

Authors:  Trishe Y-M Leong; Anthony S-Y Leong
Journal:  HPB (Oxford)       Date:  2005       Impact factor: 3.647

2.  Preventing hepatitis B in people in close contact with hepatocellular carcinoma patients.

Authors:  M W Oberle; C N Shapiro; A P Lanier
Journal:  Public Health Rep       Date:  1997 Jan-Feb       Impact factor: 2.792

Review 3.  KASL clinical practice guidelines: management of chronic hepatitis B.

Authors: 
Journal:  Clin Mol Hepatol       Date:  2016-03-28

4.  KASL Clinical Practice Guidelines: Management of chronic hepatitis B.

Authors: 
Journal:  Clin Mol Hepatol       Date:  2012-06-26

5.  Familial clustering of hepatocellular carcinoma in HBsAg-positive patients in the United States.

Authors:  Myron John Tong; Thatcher Thi Huynh; Surachate Siripongsakun
Journal:  Hepatol Int       Date:  2013-07-17       Impact factor: 6.047

6.  Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinomas.

Authors:  K H Buetow; V C Sheffield; M Zhu; T Zhou; F M Shen; O Hino; M Smith; B J McMahon; A P Lanier; W T London
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

Review 7.  Hepatocellular Carcinoma: Causes, Mechanism of Progression and Biomarkers.

Authors:  Amit Kumar Singh; Ramesh Kumar; Abhay K Pandey
Journal:  Curr Chem Genom Transl Med       Date:  2018-06-29

8.  Familial hepatocellular carcinoma in an endemic area: two case reports.

Authors:  Elroy P Weledji; Dickson S Nsagha; George Enoworock; Maurice Mouladje
Journal:  BMC Res Notes       Date:  2015-09-05

Review 9.  Familial hepatocellular carcinoma: 'A model for studying preventive and therapeutic measures'.

Authors:  Elroy Patrick Weledji
Journal:  Ann Med Surg (Lond)       Date:  2018-09-28
  9 in total

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