| Literature DB >> 1655480 |
Abstract
In isolated, perfused rabbit ear artery bradykinin, like [Met5]enkephalin and angiotensin II, inhibited neurogenic constrictions in concentrations lower than 10(-8) M without affecting the responses to exogenous norepinephrine. The IC50 value of bradykinin was 1.95 x 10(-10) M. The inhibitory action of bradykinin and angiotensin II but not of [Met5]enkephalin was reduced or even reversed by indomethacin pretreatment, suggesting that endogenous prostanoids are involved.Entities:
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Year: 1991 PMID： 1655480 DOI： 10.1016/0014-2999(91)90567-a
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432