Literature DB >> 165545

Resticted growth of human cytomegalovirus in UV-irradiated WI-38 human fibroblasts.

T Furukawa, S Tanaka, S A Plotkin.   

Abstract

The growth of human CMV was inhibited by uv irradiation of cells prior to infection or during the 48-hr latent period of virus replication but not after virus synthesis began. The duration of uv exposure sufficient to inhibit CMV replication was insufficient to inhibit replication of Herpes simplex and did not prevent uninfected cells from dividing normally. The effect of uv irradiation on CMV replication may have been mediated through prevention of the virus on host cell RNA(s) synthesis.

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Year:  1975        PMID: 165545     DOI: 10.3181/00379727-148-38726

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  7 in total

1.  Enhancement by calcium of the detection of cytomegalovirus in cells treated with dexamethasone and dimethyl sulfoxide.

Authors:  P G West; W W Baker
Journal:  J Clin Microbiol       Date:  1990-08       Impact factor: 5.948

2.  Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny.

Authors:  Jessica McArdle; Xenia L Schafer; Joshua Munger
Journal:  J Virol       Date:  2010-11-17       Impact factor: 5.103

3.  Stanley Plotkin: the bright spark of cytomegalovirus vaccines.

Authors:  Edward S Mocarski
Journal:  Med Microbiol Immunol       Date:  2015-03-20       Impact factor: 3.402

4.  Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.

Authors:  Cody M Spencer; Xenia L Schafer; Nathaniel J Moorman; Joshua Munger
Journal:  J Virol       Date:  2011-04-06       Impact factor: 5.103

5.  Enhanced detection of cytomegalovirus in confluent MRC-5 cells treated with dexamethasone and dimethyl sulfoxide.

Authors:  P G West; B Aldrich; R Hartwig; G J Haller
Journal:  J Clin Microbiol       Date:  1988-12       Impact factor: 5.948

6.  Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins.

Authors:  Miguel Gaspar; Thomas Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-13       Impact factor: 11.205

7.  Inhibition by monensin of human cytomegalovirus DNA replication.

Authors:  C J Kaiser; K Radsak
Journal:  Arch Virol       Date:  1987       Impact factor: 2.574

  7 in total

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