Literature DB >> 16554494

Cluster headache is associated with the G1246A polymorphism in the hypocretin receptor 2 gene.

M Schürks1, T Kurth, I Geissler, G Tessmann, H-C Diener, D Rosskopf.   

Abstract

The G1246A polymorphism in the gene of the hypocretin receptor 2 (HCRTR2) has been linked to the risk for cluster headache (CH). The authors examined this association in a large sample of 226 patients with CH and 266 controls from Germany. The genotype and allele distribution varied significantly between patients and controls. Homozygous carriers of the G-allele had a twofold increase in risk for CH (OR 1.97; 95% CI 1.32 to 2.92; p = 0.0007).

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Year:  2006        PMID: 16554494     DOI: 10.1212/01.wnl.0000215852.35329.34

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  27 in total

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2.  Hypothalamic regulation of headache and migraine.

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Authors:  Markus Schürks
Journal:  Curr Pain Headache Rep       Date:  2010-04

4.  Family History of Cluster Headache: A Systematic Review.

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Review 5.  Epidemiology of cluster headache.

Authors:  Susan W Broner; Joshua M Cohen
Journal:  Curr Pain Headache Rep       Date:  2009-04

Review 6.  Genetics of headache in children: where are we headed?

Authors:  Andrew D Hershey
Journal:  Curr Pain Headache Rep       Date:  2008-10

Review 7.  Genetics of migraine headache in children.

Authors:  Andrew D Hershey
Journal:  Curr Pain Headache Rep       Date:  2007-10

8.  Microelectrode recording in the posterior hypothalamic region in humans.

Authors:  Sepehr Sani; Shoichi Shimamoto; Robert S Turner; Nadja Levesque; Philip A Starr
Journal:  Neurosurgery       Date:  2009-03       Impact factor: 4.654

9.  Evidence for an association between migraine and the hypocretin receptor 1 gene.

Authors:  Innocenzo Rainero; Elisa Rubino; Salvatore Gallone; Pierpaola Fenoglio; Luigi Rocco Picci; Laura Giobbe; Luca Ostacoli; Lorenzo Pinessi
Journal:  J Headache Pain       Date:  2011-02-23       Impact factor: 7.277

Review 10.  Association between the G1246A polymorphism of the hypocretin receptor 2 gene and cluster headache: a meta-analysis.

Authors:  Innocenzo Rainero; Elisa Rubino; Walter Valfrè; Salvatore Gallone; Paola De Martino; Erika Zampella; Lorenzo Pinessi
Journal:  J Headache Pain       Date:  2007-06-11       Impact factor: 7.277

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