| Literature DB >> 165544 |
Abstract
Exposure of WI-38 cells to ascorbic acid plus glutathione mixtures in growth medium for 2 days prior to infection with rhinovirus serotype 20 and during virus replication suppressed multicyclic but not single-cycle growth of the virus. Multicyclic growth was suppressed over the range of multiplicity of infection (m.o.i.) of 4 times 10-minus 1 minus 4 times 10-minus 4 PFU/cell. There was some suggestion that, in the presence of ascorbic acid plus glutathione, interferon was produced at the highest m.o.i. tested but at barely detectable levels.Entities:
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Year: 1975 PMID： 165544 DOI： 10.3181/00379727-148-38724
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN： 0037-9727