Literature DB >> 165541

Enhancement of interferon production in vitro: a property of tilorone-poly rL:rC/DEAE-Dextran.

J W Groelke, K P Camyre, G D Mayer.   

Abstract

Tilorone and Poly rI:rC, in the presence of DEAE-dextran, were found to exhibit a marked synergism with respect to the induction of interferon in L929 and primary mouse embryo fibroblasts, but not human foreskin fibroblasts, in cell cultures. The degree of synergism was proportional to the concentrations of tilorone and Poly rI:rC and was influenced by the times of addition of the compounds relative to each other.

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Year:  1975        PMID: 165541     DOI: 10.3181/00379727-148-38685

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  1 in total

1.  Enhancement of human interferon production by neutral red and chloroquine: analysis of inhibition of protein degradation and macromolecular synthesis.

Authors:  P B Sehgal; I Tamm; J Vilcek
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

  1 in total

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