Literature DB >> 16552088

Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice.

Yang Re Kim1, Shaun R Brinsmade, Zheng Yang, Jorge Escalante-Semerena, Joshua Fierer.   

Abstract

A phosphotransacetylase (pta) mutant of Salmonella enterica serovar Typhimurium was attenuated in mice but survived normally in macrophages. Complementation of the pta mutation in trans restored virulence. An isocitrate lyase (aceA) mutant was virulent, so the inability to use acetate as a sole carbon source does not explain the phenotype.

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Year:  2006        PMID： 16552088      PMCID： PMC1418904          DOI： 10.1128/IAI.74.4.2498-2502.2006

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  23 in total

1.  Acetyl phosphate-dependent activation of a mutant PhoP response regulator that functions independently of its cognate sensor kinase.

Authors:  S Chamnongpol; E A Groisman
Journal:  J Mol Biol       Date:  2000-07-07       Impact factor: 5.469

2.  The enzymic interconversion of acetate and acetyl-coenzyme A in Escherichia coli.

Authors:  T D Brown; M C Jones-Mortimer; H L Kornberg
Journal:  J Gen Microbiol       Date:  1977-10

3.  Deoxyribonucleic acid sequence of araBAD promoter mutants of Escherichia coli.

Authors:  A H Horwitz; C Morandi; G Wilcox
Journal:  J Bacteriol       Date:  1980-05       Impact factor: 3.490

4.  In vitro conversion of propionate to pyruvate by Salmonella enterica enzymes: 2-methylcitrate dehydratase (PrpD) and aconitase Enzymes catalyze the conversion of 2-methylcitrate to 2-methylisocitrate.

Authors:  A R Horswill; J C Escalante-Semerena
Journal:  Biochemistry       Date:  2001-04-17       Impact factor: 3.162

5.  Propionyl coenzyme A is a common intermediate in the 1,2-propanediol and propionate catabolic pathways needed for expression of the prpBCDE operon during growth of Salmonella enterica on 1,2-propanediol.

Authors:  Sergio Palacios; Vincent J Starai; Jorge C Escalante-Semerena
Journal:  J Bacteriol       Date:  2003-05       Impact factor: 3.490

6.  Intestinal short-chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA.

Authors:  Sara D Lawhon; Russell Maurer; Mitsu Suyemoto; Craig Altier
Journal:  Mol Microbiol       Date:  2002-12       Impact factor: 3.501

7.  Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence.

Authors:  Ernesto J Muñoz-Elías; John D McKinney
Journal:  Nat Med       Date:  2005-05-15       Impact factor: 53.440

8.  Residues C123 and D58 of the 2-methylisocitrate lyase (PrpB) enzyme of Salmonella enterica are essential for catalysis.

Authors:  T L Grimek; H Holden; I Rayment; J C Escalante-Semerena
Journal:  J Bacteriol       Date:  2003-08       Impact factor: 3.490

9.  Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine.

Authors:  V J Starai; I Celic; R N Cole; J D Boeke; J C Escalante-Semerena
Journal:  Science       Date:  2002-12-20       Impact factor: 47.728

10.  Delineation of upstream signaling events in the salmonella pathogenicity island 2 transcriptional activation pathway.

Authors:  Charles C Kim; Stanley Falkow
Journal:  J Bacteriol       Date:  2004-07       Impact factor: 3.490
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  11 in total

Review 1.  Physiologically relevant small phosphodonors link metabolism to signal transduction.

Authors:  Alan J Wolfe
Journal:  Curr Opin Microbiol       Date:  2010-01-29       Impact factor: 7.934

2.  Biochemical and Kinetic Characterization of the Eukaryotic Phosphotransacetylase Class IIa Enzyme from Phytophthora ramorum.

Authors:  Tonya Taylor; Cheryl Ingram-Smith; Kerry S Smith
Journal:  Eukaryot Cell       Date:  2015-05-08

3.  Uropathogenic Escherichia coli CFT073 is adapted to acetatogenic growth but does not require acetate during murine urinary tract infection.

Authors:  Andrew T Anfora; David K Halladin; Brian J Haugen; Rodney A Welch
Journal:  Infect Immun       Date:  2008-10-06       Impact factor: 3.441

4.  Convergent molecular evolution of genomic cores in Salmonella enterica and Escherichia coli.

Authors:  Sujay Chattopadhyay; Sandip Paul; Dagmara I Kisiela; Elena V Linardopoulou; Evgeni V Sokurenko
Journal:  J Bacteriol       Date:  2012-07-13       Impact factor: 3.490

5.  Simultaneous Identification of Potential Pathogenicity Factors of Mycoplasma agalactiae in the Natural Ovine Host by Negative Selection.

Authors:  Shivanand Hegde; Shrilakshmi Hegde; Martina Zimmermann; Martina Flöck; Joachim Spergser; Renate Rosengarten; Rohini Chopra-Dewasthaly
Journal:  Infect Immun       Date:  2015-04-27       Impact factor: 3.441

6.  The Aeromonas salmonicida subsp. salmonicida exoproteome: determination of the complete repertoire of Type-Three Secretion System effectors and identification of other virulence factors.

Authors:  Philippe Vanden Bergh; Manfred Heller; Sophie Braga-Lagache; Joachim Frey
Journal:  Proteome Sci       Date:  2013-09-27       Impact factor: 2.480

7.  Comparative Genomics of Mycoplasma bovis Strains Reveals That Decreased Virulence with Increasing Passages Might Correlate with Potential Virulence-Related Factors.

Authors:  Muhammad A Rasheed; Jingjing Qi; Xifang Zhu; He Chenfei; Harish Menghwar; Farhan A Khan; Gang Zhao; Muhammad Zubair; Changmin Hu; Yingyu Chen; Huanchun Chen; Aizhen Guo
Journal:  Front Cell Infect Microbiol       Date:  2017-05-11       Impact factor: 5.293

8.  Salmonella enterica Requires Lipid Metabolism Genes To Replicate in Proinflammatory Macrophages and Mice.

Authors:  Abigail L Reens; Toni A Nagy; Corrella S Detweiler
Journal:  Infect Immun       Date:  2019-12-17       Impact factor: 3.441

9.  Optimized two-dimensional thin layer chromatography to monitor the intracellular concentration of acetyl phosphate and other small phosphorylated molecules.

Authors:  David H Keating; Ana Shulla; Adam H Klein; Alan J Wolfe
Journal:  Biol Proced Online       Date:  2008-03-03       Impact factor: 3.244

10.  Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition.

Authors:  Tristan Lefébure; Michael J Stanhope
Journal:  Genome Biol       Date:  2007       Impact factor: 13.583
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