| Literature DB >> 16552076 |
Jesse Wells1, Constantine G Haidaris, Terry W Wright, Francis Gigliotti.
Abstract
Mice immunized with recombinant mouse Pneumocystis carinii antigen A12-thioredoxin fusion protein developed an antibody response that recognized P. carinii antigens, as determined by Western blotting and immunofluorescence analysis. Compared to mice immunized with thioredoxin alone, mice immunized with A12-thioredoxin had significantly reduced lung P. carinii burdens after CD4+ T-cell depletion and challenge with P. carinii.Entities:
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Year: 2006 PMID: 16552076 PMCID: PMC1418926 DOI: 10.1128/IAI.74.4.2446-2448.2006
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441