Literature DB >> 16550284

Nickel-catalyzed asymmetric alpha-arylation of ketone enolates.

Guoshu Chen1, Fuk Yee Kwong, Hoi On Chan, Wing-Yiu Yu, Albert S C Chan.   

Abstract

An atropisomeric dipyridyldiphosphine, P-Phos, can effect highly enantioselective Ni-catalyzed alpha-arylation of ketone enolates with aryl halides to install an all-carbon quaternary stereogenic center in up to 98% ee and excellent yields.

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Year:  2006        PMID： 16550284     DOI： 10.1039/b601691j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Enantioselective construction of all-carbon quaternary centers by branch-selective Pd-catalyzed allyl-allyl cross-coupling.

Authors:  Ping Zhang; Hai Le; Robert E Kyne; James P Morken
Journal:  J Am Chem Soc       Date:  2011-06-07       Impact factor: 15.419

2.  Nickel/bis(oxazoline)-catalyzed asymmetric Kumada reactions of alkyl electrophiles: cross-couplings of racemic alpha-bromoketones.

Authors:  Sha Lou; Gregory C Fu
Journal:  J Am Chem Soc       Date:  2010-02-03       Impact factor: 15.419

3.  Catalytic asymmetric cross-couplings of racemic alpha-bromoketones with arylzinc reagents.

Authors:  Pamela M Lundin; Jorge Esquivias; Gregory C Fu
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

4.  Enantioselective alpha-arylation of ketones with aryl triflates catalyzed by difluorphos complexes of palladium and nickel.

Authors:  Xuebin Liao; Zhiqiang Weng; John F Hartwig
Journal:  J Am Chem Soc       Date:  2007-12-13       Impact factor: 15.419

5.  Catalytic asymmetric alkylation of substituted isoflavanones.

Authors:  Antoinette E Nibbs; Amanda-Lauren Baize; Rachel M Herter; Karl A Scheidt
Journal:  Org Lett       Date:  2009-09-03       Impact factor: 6.005

6.  Computational Analysis of Enantioselective Pd-Catalyzed α-Arylation of Ketones.

Authors:  Manuel Orlandi; Giulia Licini
Journal:  J Org Chem       Date:  2020-08-19       Impact factor: 4.354
  6 in total

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