| Literature DB >> 16550277 |
Jonathan Clayden1, Christopher C Stimson, Martine Keenan.
Abstract
Directed metallation and sulfinylation yields sulfoxides which undergo ipso nucleophilic aromatic substitution with tertiary and secondary alkyllithiums, giving aromatic rings bearing alkyl groups generally incompatible with directed metallation methods and with regioselectivity complementary with classical Friedel-Crafts substitution.Entities:
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Year: 2006 PMID： 16550277 DOI： 10.1039/b600181e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222