Literature DB >> 16548994

Pathology of supraclavicular lymphadenopathy in Chandigarh, north India: an audit of 200 cases diagnosed by needle aspiration.

N Gupta1, A Rajwanshi, R Srinivasan, R Nijhawan.   

Abstract

OBJECTIVE: Fine needle aspiration cytology (FNAC) of lymph nodes can be used routinely as a first-line diagnostic test. The majority of studies reveal a malignant cause for palpable supraclavicular lymph nodes. The present audit further emphasizes the use of FNAC as a first-line investigation for the evaluation of enlarged supraclavicular lymph nodes.
METHODS: A total of 200 cases of palpable supraclavicular lymph node(s) were included in the present study.
RESULTS: Left supraclavicular lymph nodes were found to be more commonly involved (59.5% cases). Sixty-four per cent cases showed metastatic deposits and 13.5% cases were diagnosed as tuberculosis. Ten per cent cases showed reactive lymphoid hyperplasia; 0.5% (one) case showed only necrosis and on autopsy, a microscopic focus of choriocarcinoma was found in the testis. In 7.5% cases, diagnostic material could not be aspirated despite repeated attempts. Common metastatic tumours were from lung (22% cases), breast (16.4% cases), cervix (11% cases) and oesophagus (8.6% cases). In 13.3% cases the primary site was unknown and the diagnosis of malignancy first came from FNAC.
CONCLUSION: The present study further highlights the importance of FNAC as a first-line diagnostic modality in the evaluation of supraclavicular lymphadenopathy. A full history, radiological findings and immunochemistry in difficult cases can help to arrive at a definitive diagnosis.

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Year:  2006        PMID: 16548994     DOI: 10.1111/j.1365-2303.2006.00285.x

Source DB:  PubMed          Journal:  Cytopathology        ISSN: 0956-5507            Impact factor:   2.073


  7 in total

1.  Fine needle aspiration cytology of supraclavicular lymph nodes: Our experience over a three-year period.

Authors:  Sumit Mitra; Suchandra Ray; Pradip K Mitra
Journal:  J Cytol       Date:  2011-07       Impact factor: 1.000

2.  Misdiagnosis of left supraclavicular lymph node metastasis of hepatocellular carcinoma: a case report.

Authors:  Tao Liu; Jun-Fang Gao; Yong-Xiang Yi; Hai Ding; Wei Liu
Journal:  World J Gastroenterol       Date:  2013-02-14       Impact factor: 5.742

Review 3.  Diagnosis and management of acute cholangitis.

Authors:  John G Lee
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2009-08-04       Impact factor: 46.802

4.  FNAC in the diagnosis of lymph node malignancies: A simple and sensitive tool.

Authors:  Anne R Wilkinson; Sadhana D Mahore; Sabiha A Maimoon
Journal:  Indian J Med Paediatr Oncol       Date:  2012-01

5.  Right cervical lymphadenopathy: a rare presentation of metastatic hepatocellular carcinoma.

Authors:  Irappa Madabhavi; Apurva Patel; Mukesh Choudhary; Asha Anand; Harsha Panchal; Sonia Parikh
Journal:  Gastroenterol Hepatol Bed Bench       Date:  2014

6.  A case of complicated silicosis with a complex clinical course in a glass manufacturing worker.

Authors:  Hee-Seok Yang; Jung-Il Kim; Byeong-Jin Ye; Tae-Jun Yoo; Sun-Woo Lee; Kap-Yeol Jung
Journal:  Ann Occup Environ Med       Date:  2014-05-15

7.  Application of Ultrasound-Guided Core Biopsy to Minimal-Invasively Diagnose Supraclavicular Fossa Tumors and Minimize the Requirement of Invasive Diagnostic Surgery.

Authors:  Chun-Nan Chen; Che-Yi Lin; Fan-Hsiang Chi; Chen-Han Chou; Ya-Ching Hsu; Yen-Lin Kuo; Chih-Feng Lin; Tseng-Cheng Chen; Cheng-Ping Wang; Pei-Jen Lou; Jenq-Yuh Ko; Tzu-Yu Hsiao; Tsung-Lin Yang
Journal:  Medicine (Baltimore)       Date:  2016-01       Impact factor: 1.889

  7 in total

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