| Literature DB >> 1654896 |
E Lehmberg1, R B Ota, K Furuya, D S King, S W Applebaum, H J Ferenz, D A Schooley.
Abstract
We have isolated a peptide from brains and corpora cardiaca of Locusta migratoria which is immunologically related to the diuretic hormone of Manduca sexta. We determined its structure as a 46 amino acid linear peptide with 43-50% identity to the M. sexta hormone. Moreover, we showed that the new peptide functions as a diuretic hormone in L. migratoria, stimulating urine production by Malpighian tubules and elevating levels of cAMP in tubules.Entities:
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Year: 1991 PMID: 1654896 DOI: 10.1016/0006-291x(91)91923-z
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575