Literature DB >> 16548918

A case of hepatosplenic gamma-delta T-cell lymphoma with a transient response to fludarabine and alemtuzumab.

S Mittal1, B J Milner, P W Johnston, D J Culligan.   

Abstract

Hepatosplenic gamma-delta T-cell lymphoma is a rare, usually fatal lymphoma and available literature on management is sparse. Allografting is probably the only curative option. We describe a further case with a dramatic, though transient response to Fludarabine and Alemtuzumab combination, following a failure of conventional chemotherapy. Given the dreadful prognosis with conventional chemotherapy, it is a regimen worth pursuing as a disease reduction strategy prior to allograft where appropriate.

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Year:  2006        PMID: 16548918     DOI: 10.1111/j.1600-0609.2006.00646.x

Source DB:  PubMed          Journal:  Eur J Haematol        ISSN: 0902-4441            Impact factor:   2.997


  15 in total

1.  A rare cause of Fever, hepatosplenomegaly, and thrombocytopenia: hepatosplenic gamma/delta T-cell lymphoma.

Authors:  Murat Albayrak; Ozlem Sahin Balcik; Saadet Alan; Suleyman Lütfü Dıncer; Meltem Kurt Yüksel; Aynur Albayrak
Journal:  Pathol Oncol Res       Date:  2011-01-01       Impact factor: 3.201

Review 2.  Risks and benefits of biologic therapy for inflammatory bowel diseases.

Authors:  Geert D'Haens
Journal:  Gut       Date:  2007-05       Impact factor: 23.059

3.  Aggressive Lymphomas Diagnosed in the Bone Marrow: Two Illustrative Cases.

Authors:  Rekha Bhat; Swati Pai; Kunal Das; Ashish Dixit
Journal:  Indian J Hematol Blood Transfus       Date:  2015-02-26       Impact factor: 0.900

4.  Hepatosplenic T-cell lymphoma arising in patients with immunodysregulatory disorders: a study of 7 patients who did not receive tumor necrosis factor-α inhibitor therapy and literature review.

Authors:  Mariko Yabe; L Jeffrey Medeiros; Yahya Daneshbod; Masoud Davanlou; Carlos E Bueso-Ramos; Elisa J Moran; Ken H Young; Roberto N Miranda
Journal:  Ann Diagn Pathol       Date:  2016-10-18       Impact factor: 2.090

Review 5.  Gamma-delta T-cell lymphomas.

Authors:  Claudio Tripodo; Emilio Iannitto; Ada Maria Florena; Carlo Ennio Pucillo; Pier Paolo Piccaluga; Vito Franco; Stefano Aldo Pileri
Journal:  Nat Rev Clin Oncol       Date:  2009-11-10       Impact factor: 66.675

Review 6.  Hepatosplenic T-cell lymphoma: a rare but challenging entity.

Authors:  Barbara Pro; Pamela Allen; Amir Behdad
Journal:  Blood       Date:  2020-10-29       Impact factor: 22.113

Review 7.  Hepatosplenic T-cell lymphoma in a patient with Crohn's disease.

Authors:  Florian Beigel; Matthias Jürgens; Cornelia Tillack; Marion Subklewe; Doris Mayr; Burkhard Göke; Stephan Brand; Thomas Ochsenkühn
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2009-07       Impact factor: 46.802

8.  Intensive induction chemotherapy followed by early high-dose therapy and hematopoietic stem cell transplantation results in improved outcome for patients with hepatosplenic T-cell lymphoma: a single institution experience.

Authors:  Martin H Voss; Matthew A Lunning; Jocelyn C Maragulia; Esperanza B Papadopoulos; Jenna Goldberg; Andrew D Zelenetz; Steven M Horwitz
Journal:  Clin Lymphoma Myeloma Leuk       Date:  2012-10-27

9.  Sustained first remission in an adolescent with hepatosplenic T-cell lymphoma treated with T-cell leukemia induction, nucleoside analog-based consolidation, and early hematopoietic stem cell transplant.

Authors:  Eric Schafer; Allen Chen; Robert J Arceci
Journal:  Pediatr Blood Cancer       Date:  2009-12       Impact factor: 3.167

10.  The Outcome of HyperCVAD Combined with Alemtuzumab for the Treatment of Aggressive T-Cell and NK-Cell Neoplasms.

Authors:  Jew Win Kuan; Kian Meng Chang; Ngee Siang Lau; Purushothaman Visalachy; Sen Mui Tan; Tee Chuan Ong; Anselm Ting Su
Journal:  Indian J Hematol Blood Transfus       Date:  2011-06-05       Impact factor: 0.900

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