| Literature DB >> 16547577 |
Wej Choochote1, Udom Chaithong, Kittichai Kamsuk, Eumporn Rattanachanpichai, Atchariya Jitpakdi, Pongsri Tippawangkosol, Dana Chaiyasit, Daruna Champakaew, Benjawan Tuetun, Benjawan Pitasawat.
Abstract
Three Piper species, Piper longum, P. ribesoides and P. sarmentosum, were selected for investigation of adulticidal potential against Stegomyia aegypti, a main vector of dengue and dengue haemorrhagic fever. Successive extraction by maceration with 95% ethanol showed percentage yields of ethanolic extracts, which derived from P. longum, P. ribesoides and P. sarmentosum, of 8.89, 3.21 and 5.30% (w/w), respectively. All Piper extracts illustrated an impressive adulticidal activity when tested against female mosquitoes by topical application. The susceptibility of St. aegypti females to ethanol-extracted Piper was dose dependent and varied among the plant species. The highest adulticidal effect was established from P. sarmentosum, followed by P. ribesoides and P. longum, with LD50 values of 0.14, 0.15 and 0.26 microg/female, respectively. The potential of these Piper species, as possible mosquitocides, established convincing activity for further researches to develop natural substances for combat against adult mosquitoes.Entities:
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Year: 2006 PMID： 16547577 DOI： 10.1590/s0036-46652006000100007
Source DB: PubMed Journal: Rev Inst Med Trop Sao Paulo ISSN： 0036-4665 Impact factor: 1.846