Literature DB >> 16546636

Correlation and comparison of body mass index on hemodynamics in hypertensive and normotensive patients undergoing intravenous sedation.

Joseph E Cillo1, Richard Finn.   

Abstract

PURPOSE: The purpose of this project was to retrospectively compare and correlate body mass index (BMI) and hemodynamics in hypertensive and normotensive patients undergoing intravenous sedation for dentoalveolar surgery. PATIENTS AND METHODS: A retrospective chart analysis of 263 consecutive male patients undergoing intravenous (IV) sedation for dentoalveolar surgery was divided into 5 BMI groups: underweight, normal weight, overweight, obese, extremely obese. Data recorded were noninvasive baseline and intraoperative hemodynamic measurements at 5-minute intervals for systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), pulse pressure (PP), and pulse (P). Statistical analysis of mean values between groups was carried out using multivariate linear regression analysis, Pearson's correlation coefficient, and Student's t test and found significant for P < .05.
RESULTS: Average hemodynamic values for normotensive patients were significantly lower for all groups except for pulse in the normal group, pulse in the obese group, and DBP in the extremely obese group. For normotensive patients, there were statistically significant strong positive correlation for elevated BMI and increased baseline changes in SBP and PP. For the hypertensive group, there was a statistically significant moderate positive correlation for elevated BMI and increased baseline changes in PP and statistically significant strong positive correlation for baseline changes in MAP. Baseline changes were significant for greater increases in SBP and decreases in DBP and MAP in the underweight hypertensive group. Significant increases from baseline in the normotensive group were for PP in the normal BMI group and for pulse in the obese group. All baseline changes, with the exception of normotensive underweight SBP (+26.7%) and hypertensive PP (+23.9%), were within +/-20% of baseline (range, -12.2% to +17.4%).
CONCLUSION: In general, normotensive patients in this study had lower average hemodynamic values than hypertensive patients in all BMI groups. Great variability was seen in baseline changes for all BMI groups, but a substantial majority of changes were within +/-20% of baseline. There were statistically significant moderate and positive correlations in BMI for changes from baseline for several hemodynamic measurements. Intravenous sedation for oral and maxillofacial surgery procedures maintains a stable hemodynamic state in hypertensive and normotensive patients regardless of BMI.

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Year:  2006        PMID: 16546636     DOI: 10.1016/j.joms.2005.12.009

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  2 in total

1.  Safety of adjunct pre-emptive intravenous tramadol with midazolam sedation for third molar surgery.

Authors:  Lars B Eriksson; Åke Tegelberg
Journal:  Oral Maxillofac Surg       Date:  2015-04-30

2.  Risk factor analysis of additional administration of sedative agent and patient dissatisfaction in intravenous conscious sedation using midazolam for third molar extraction.

Authors:  Dong-Whan Shin; Jin-Yong Cho; Yoon-Sic Han; Hye-Young Sim; Hee-Sun Kim; Da-Un Jung; Ho Lee
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2017-08-24
  2 in total

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