Literature DB >> 1654458

The nucleotide sequence, 5' end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript.

P R Krause1, J M Ostrove, S E Straus.   

Abstract

The sequence of the herpes simplex virus type 2 (HSV-2) latency-associated transcript (LAT) region resembles that of HSV-1 only where the LATs overlap ICP0 and in the putative promoter region. Otherwise, the LAT 5' ends, kinetics of expression, and promoter elements are mostly conserved between HSV-1 and HSV-2. The remaining differences between the LATs could contribute to each virus's distinctive pattern of reactivation.

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Year:  1991        PMID: 1654458      PMCID: PMC249080     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  28 in total

1.  The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.

Authors:  D A Leib; K C Nadeau; S A Rundle; P A Schaffer
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

2.  Herpes simplex virus latency-associated transcript is a stable intron.

Authors:  M J Farrell; A T Dobson; L T Feldman
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

3.  In vitro promoter activity associated with the latency-associated transcript gene of herpes simplex virus type 1.

Authors:  J Zwaagstra; H Ghiasi; A B Nesburn; S L Wechsler
Journal:  J Gen Virol       Date:  1989-08       Impact factor: 3.891

4.  Identification of the latency-associated transcript promoter by expression of rabbit beta-globin mRNA in mouse sensory nerve ganglia latently infected with a recombinant herpes simplex virus.

Authors:  A T Dobson; F Sederati; G Devi-Rao; W M Flanagan; M J Farrell; J G Stevens; E K Wagner; L T Feldman
Journal:  J Virol       Date:  1989-09       Impact factor: 5.103

5.  Physical characterization of the herpes simplex virus latency-associated transcript in neurons.

Authors:  E K Wagner; G Devi-Rao; L T Feldman; A T Dobson; Y F Zhang; W M Flanagan; J G Stevens
Journal:  J Virol       Date:  1988-04       Impact factor: 5.103

6.  Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia.

Authors:  W J Mitchell; S L Deshmane; A Dolan; D J McGeoch; N W Fraser
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

7.  Characterization of herpes simplex virus type 2 latency-associated transcription in human sacral ganglia and in cell culture.

Authors:  K D Croen; J M Ostrove; L Dragovic; S E Straus
Journal:  J Infect Dis       Date:  1991-01       Impact factor: 5.226

8.  Detection and characterization of latent HSV RNA by in situ and northern blot hybridization in guinea pigs.

Authors:  R L Burke; K Hartog; K D Croen; J M Ostrove
Journal:  Virology       Date:  1991-04       Impact factor: 3.616

9.  Prominence of the herpes simplex virus latency-associated transcript in trigeminal ganglia from seropositive humans.

Authors:  J G Stevens; L Haarr; D D Porter; M L Cook; E K Wagner
Journal:  J Infect Dis       Date:  1988-07       Impact factor: 5.226

Review 10.  The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

Authors:  D J McGeoch; M A Dalrymple; A J Davison; A Dolan; M C Frame; D McNab; L J Perry; J E Scott; P Taylor
Journal:  J Gen Virol       Date:  1988-07       Impact factor: 3.891

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  22 in total

1.  Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes.

Authors:  K Wang; L Pesnicak; S E Straus
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

2.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

3.  Regulation of Herpes Simplex Virus Glycoprotein-Induced Cascade of Events Governing Cell-Cell Fusion.

Authors:  Doina Atanasiu; Wan Ting Saw; Roselyn J Eisenberg; Gary H Cohen
Journal:  J Virol       Date:  2016-11-14       Impact factor: 5.103

Review 4.  Experimental investigation of herpes simplex virus latency.

Authors:  E K Wagner; D C Bloom
Journal:  Clin Microbiol Rev       Date:  1997-07       Impact factor: 26.132

5.  Downstream regulatory elements increase acute and latent herpes simplex virus type 2 latency-associated transcript expression but do not influence recurrence phenotype or establishment of latency.

Authors:  T Yoshikawa; L R Stanberry; N Bourne; P R Krause
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

6.  cis-acting elements involved in transcriptional regulation of the herpes simplex virus type 1 latency-associated promoter 1 (LAP1) in vitro and in vivo.

Authors:  K Soares; D Y Hwang; R Ramakrishnan; M C Schmidt; D J Fink; J C Glorioso
Journal:  J Virol       Date:  1996-08       Impact factor: 5.103

7.  Herpes Simplex Virus 2 Latency-Associated Transcript (LAT) Region Mutations Do Not Identify a Role for LAT-Associated MicroRNAs in Viral Reactivation in Guinea Pig Genital Models.

Authors:  Yoshiki Kawamura; Marta Bosch-Marce; Shuang Tang; Amita Patel; Philip R Krause
Journal:  J Virol       Date:  2018-06-29       Impact factor: 5.103

8.  Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts.

Authors:  K Wang; P R Krause; S E Straus
Journal:  J Virol       Date:  1995-05       Impact factor: 5.103

9.  Involvement of a high-mobility-group protein in the transcriptional activity of herpes simplex virus latency-active promoter 2.

Authors:  S W French; M C Schmidt; J C Glorioso
Journal:  Mol Cell Biol       Date:  1996-10       Impact factor: 4.272

10.  Varicella-zoster virus DNA polymerase and major DNA-binding protein genes have overlapping divergent promoters.

Authors:  J L Meier; S E Straus
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

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