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Literature DB >> 16543936

The versatile interactions of p53 with DNA: when flexibility serves specificity.

E Kim¹, W Deppert.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2006 PMID： 16543936 DOI： 10.1038/sj.cdd.4401909

Source DB: PubMed Journal: Cell Death Differ ISSN： 1350-9047 Impact factor: 15.828

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18 in total

1. Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.

Authors: Timo Quante; Benjamin Otto; Marie Brázdová; Iva Kejnovská; Wolfgang Deppert; Genrich V Tolstonog
Journal: Cell Cycle Date: 2012-08-21 Impact factor: 4.534

2. Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

Authors: Krassimira Botcheva; Sean R McCorkle; W R McCombie; John J Dunn; Carl W Anderson
Journal: Cell Cycle Date: 2011-12-15 Impact factor: 4.534

3. Human DHX9 helicase unwinds triple-helical DNA structures.

Authors: Aklank Jain; Albino Bacolla; Prasun Chakraborty; Frank Grosse; Karen M Vasquez
Journal: Biochemistry Date: 2010-08-24 Impact factor: 3.162

Review 4. The expanding universe of p53 targets.

Authors: Daniel Menendez; Alberto Inga; Michael A Resnick
Journal: Nat Rev Cancer Date: 2009-10 Impact factor: 60.716

5. Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences.

Authors: Daniel Menendez; Alberto Inga; Michael A Resnick
Journal: Proc Natl Acad Sci U S A Date: 2010-01-04 Impact factor: 11.205

6. Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells.

Authors: Ella L Kim; Robin Wüstenberg; Anne Rübsam; Christoph Schmitz-Salue; Gabriele Warnecke; Eva-Maria Bücker; Nadine Pettkus; Daniel Speidel; Veit Rohde; Walter Schulz-Schaeffer; Wolfgang Deppert; Alf Giese
Journal: Neuro Oncol Date: 2010-01-27 Impact factor: 12.300

The versatile interactions of p53 with DNA: when flexibility serves specificity.

1. Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.

2. Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

3. Human DHX9 helicase unwinds triple-helical DNA structures.

Review 4. The expanding universe of p53 targets.

5. Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences.

6. Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells.

Review 7. When mutants gain new powers: news from the mutant p53 field.

Review 8. Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics.

9. Lysine120 interactions with p53 response elements can allosterically direct p53 organization.

10. Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway.