Literature DB >> 16543536

Cerebellar hypermetabolism in paraneoplastic cerebellar degeneration.

K-D Choi1, J S Kim, S-H Park, Y K Kim, S E Kim, P S Smitt.   

Abstract

A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.

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Year:  2006        PMID: 16543536      PMCID: PMC2077501          DOI: 10.1136/jnnp.2005.075325

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  10 in total

1.  Sub-acute cerebellar degeneration with anti-Yo autoantibodies: immunohistochemical analysis of the immune reaction in the central nervous system.

Authors:  B Giometto; G C Marchiori; P Nicolao; T Scaravilli; A Lion; P G Bardin; B Tavolato
Journal:  Neuropathol Appl Neurobiol       Date:  1997-12       Impact factor: 8.090

2.  Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with gastric adenocarcinoma.

Authors:  B Meglic; F Graus; A Grad
Journal:  J Neurol Sci       Date:  2001-04-01       Impact factor: 3.181

3.  Inflammatory infiltrates and complete absence of Purkinje cells in anti-Yo-associated paraneoplastic cerebellar degeneration.

Authors:  J Verschuuren; L Chuang; M K Rosenblum; F Lieberman; A Pryor; J B Posner; J Dalmau
Journal:  Acta Neuropathol       Date:  1996       Impact factor: 17.088

4.  Limbic encephalitis investigated by 18FDG-PET and 3D MRI.

Authors:  J Kassubek; F D Juengling; E U Nitzsche; C H Lücking
Journal:  J Neuroimaging       Date:  2001-01       Impact factor: 2.486

5.  Sequential MRI, SPECT and PET in respiratory syncytial virus encephalitis.

Authors:  K Hirayama; H Sakazaki; S Murakami; S Yonezawa; K Fujimoto; T Seto; K Tanaka; H Hattori; O Matsuoka; R Murata
Journal:  Pediatr Radiol       Date:  1999-04

Review 6.  Paraneoplastic syndromes.

Authors:  J O Dalmau; J B Posner
Journal:  Arch Neurol       Date:  1999-04

Review 7.  Serial 18F-fluoro-2-deoxy-D-glucose positron emission tomography and magnetic resonance imaging of paraneoplastic limbic encephalitis.

Authors:  Rainer Scheid; Thomas Lincke; Raymond Voltz; D Yves von Cramon; Osama Sabri
Journal:  Arch Neurol       Date:  2004-11

8.  Recommended diagnostic criteria for paraneoplastic neurological syndromes.

Authors:  F Graus; J Y Delattre; J C Antoine; J Dalmau; B Giometto; W Grisold; J Honnorat; P Sillevis Smitt; Ch Vedeler; J J G M Verschuuren; A Vincent; R Voltz
Journal:  J Neurol Neurosurg Psychiatry       Date:  2004-08       Impact factor: 10.154

9.  [Uncoupling of cerebellar blood flow and metabolism in paraneoplastic cerebellar degeneration: report of a case].

Authors:  S Tanaka; M Tanaka; N Wada; K Okamoto; S Hirai; K Tanaka
Journal:  Rinsho Shinkeigaku       Date:  1997-06

10.  Paraneoplastic cerebellar degeneration associated with antineuronal antibodies: analysis of 50 patients.

Authors:  Setareh Shams'ili; Joost Grefkens; Bertie de Leeuw; Martin van den Bent; Herbert Hooijkaas; Bronno van der Holt; Charles Vecht; Peter Sillevis Smitt
Journal:  Brain       Date:  2003-06       Impact factor: 13.501

  10 in total
  17 in total

1.  Unusual MRI abnormalities in anti-Yo positive "pure" paraneoplastic cerebellar degeneration.

Authors:  John C McHugh; Niall Tubridy; Conor D Collins; Michael Hutchinson
Journal:  J Neurol       Date:  2007-11-14       Impact factor: 4.849

2.  Paraneoplastic cerebellar degeneration: new insights into imaging and immunology.

Authors:  J H Rees
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-04       Impact factor: 10.154

Review 3.  Paraneoplastic syndromes of the CNS.

Authors:  Josep Dalmau; Myrna R Rosenfeld
Journal:  Lancet Neurol       Date:  2008-04       Impact factor: 44.182

4.  Consensus paper: radiological biomarkers of cerebellar diseases.

Authors:  Leonardo Baldarçara; Stuart Currie; M Hadjivassiliou; Nigel Hoggard; Allison Jack; Andrea P Jackowski; Mario Mascalchi; Cecilia Parazzini; Kathrin Reetz; Andrea Righini; Jörg B Schulz; Alessandra Vella; Sara Jane Webb; Christophe Habas
Journal:  Cerebellum       Date:  2015-04       Impact factor: 3.847

Review 5.  Voltage gated calcium channel antibody-related neurological diseases.

Authors:  Can Ebru Bekircan-Kurt; Eda Derle Çiftçi; Aslı Tuncer Kurne; Banu Anlar
Journal:  World J Clin Cases       Date:  2015-03-16       Impact factor: 1.337

Review 6.  Role of FDG-PET in the clinical management of paraneoplastic neurological syndrome: detection of the underlying malignancy and the brain PET-MRI correlates.

Authors:  Sandip Basu; Abass Alavi
Journal:  Mol Imaging Biol       Date:  2008-02-23       Impact factor: 3.488

7.  Paraneoplastic Cerebellar Degeneration as Initial Presentation of Papillary Carcinoma of the Fallopian Tube: Evaluation and Usefulness of (18)F-FDG PET-CT. Case Report and Literature Review.

Authors:  Nayelli Ortega López; Digna Pachuca González; José Alfonso Rumoroso García; Juan Carlos García Reyna; Luis Felipe Alva López
Journal:  Nucl Med Mol Imaging       Date:  2012-10-15

Review 8.  Paraneoplastic neurological syndromes.

Authors:  F Leypoldt; K-P Wandinger
Journal:  Clin Exp Immunol       Date:  2014-03       Impact factor: 4.330

9.  Isolated cerebellar hypermetabolism on FDG PET in a case of remitted primary breast lymphoma.

Authors:  Arun Kumar Reddy; Sampath Santhosh; Bhagwant Rai Mittal; Anish Bhattacharya; Suresh C Sharma
Journal:  Indian J Nucl Med       Date:  2014-01

Review 10.  Cell-mediated immune responses in paraneoplastic neurological syndromes.

Authors:  Mikolaj Piotr Zaborowski; Slawomir Michalak
Journal:  Clin Dev Immunol       Date:  2013-12-30
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