| Literature DB >> 165431 |
Abstract
The binding of concanavqlin A to T but not B mouse spleen lymphocytes increases Ca-2+ uptake in these cells which is measurable by 45 s and complete by 1 min. Dibutyrl cyclic AMP, but not sodium azide inhibits induced Ca-2+ uptake, wheras dibutyryl cyclic GMP enhances it. B cell mitogens do not cause a similar Ca-2+ uptake in mouse B lymphocytes. The induction of increased Ca-2+ uptake by T cells is discussed in terms of gated membrane channels for Ca-2+.Entities:
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Year: 1975 PMID： 165431 DOI： 10.1038/255378a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962