Literature DB >> 16542626

Genetics of type 2 diabetes.

Mark I McCarthy1, Eleftheria Zeggini.   

Abstract

After several years of uncertain progress, the stage is now set for a transformation in understanding the genetic landscape of type 2 diabetes. Advances in genome informatics, genotyping technology, and statistical methodology, allied to availability of large-scale clinical material, are having a salutary effect on susceptibility gene discovery. The advent of genuinely genome-wide association scans and the prospects for combining genetics with high-throughput genomics are additional sources of optimism for the future.

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Year:  2006        PMID： 16542626     DOI： 10.1007/s11892-006-0026-7

Source DB:  PubMed          Journal:  Curr Diab Rep        ISSN： 1534-4827            Impact factor:   4.810


  47 in total

1.  The double helix in clinical practice.

Authors:  John I Bell
Journal:  Nature       Date:  2003-01-23       Impact factor: 49.962

2.  A haplotype map of the human genome.

Authors: 
Journal:  Nature       Date:  2005-10-27       Impact factor: 49.962

3.  Making the right associations.

Authors:  M I McCarthy; P-H Groop; T Hansen
Journal:  Diabetologia       Date:  2005-07       Impact factor: 10.122

4.  Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes.

Authors:  Jose C Florez; Marketa Sjögren; Noël Burtt; Marju Orho-Melander; Steve Schayer; Maria Sun; Peter Almgren; Ulf Lindblad; Tiinamaija Tuomi; Daniel Gaudet; Thomas J Hudson; Mark J Daly; Kristin G Ardlie; Joel N Hirschhorn; David Altshuler; Leif Groop
Journal:  Diabetes       Date:  2004-12       Impact factor: 9.461

5.  Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.

Authors:  Anna L Gloyn; Ewan R Pearson; Jennifer F Antcliff; Peter Proks; G Jan Bruining; Annabelle S Slingerland; Neville Howard; Shubha Srinivasan; José M C L Silva; Janne Molnes; Emma L Edghill; Timothy M Frayling; I Karen Temple; Deborah Mackay; Julian P H Shield; Zdenek Sumnik; Adrian van Rhijn; Jerry K H Wales; Penelope Clark; Shaun Gorman; Javier Aisenberg; Sian Ellard; Pål R Njølstad; Frances M Ashcroft; Andrew T Hattersley
Journal:  N Engl J Med       Date:  2004-04-29       Impact factor: 91.245

Review 6.  Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification.

Authors:  Mark I McCarthy
Journal:  Hum Mol Genet       Date:  2004-01-13       Impact factor: 6.150

7.  Genetic cause of hyperglycaemia and response to treatment in diabetes.

Authors:  Ewan R Pearson; Bryan J Starkey; Roy J Powell; Fiona M Gribble; Penny M Clark; Andrew T Hattersley
Journal:  Lancet       Date:  2003-10-18       Impact factor: 79.321

8.  Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies.

Authors:  A Jellema; M P A Zeegers; E J M Feskens; P C Dagnelie; R P Mensink
Journal:  Diabetologia       Date:  2003-06-18       Impact factor: 10.122

Review 9.  A comprehensive review of genetic association studies.

Authors:  Joel N Hirschhorn; Kirk Lohmueller; Edward Byrne; Kurt Hirschhorn
Journal:  Genet Med       Date:  2002 Mar-Apr       Impact factor: 8.822

10.  Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.

Authors:  David Meyre; Nabila Bouatia-Naji; Agnès Tounian; Chantal Samson; Cécile Lecoeur; Vincent Vatin; Maya Ghoussaini; Christophe Wachter; Serge Hercberg; Guillaume Charpentier; Wolfgang Patsch; François Pattou; Marie-Aline Charles; Patrick Tounian; Karine Clément; Béatrice Jouret; Jacques Weill; Betty A Maddux; Ira D Goldfine; Andrew Walley; Philippe Boutin; Christian Dina; Philippe Froguel
Journal:  Nat Genet       Date:  2005-07-17       Impact factor: 38.330
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  5 in total

1.  Sideways Glance: Genome wide association studies for type 2 diabetes mellitus.

Authors:  Yula Sambuy
Journal:  Genes Nutr       Date:  2007-12       Impact factor: 5.523

2.  A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population.

Authors:  Hiroshi Onuma; Yasuharu Tabara; Ryoichi Kawamura; Takashi Tanaka; Jun Ohashi; Wataru Nishida; Yasunori Takata; Masaaki Ochi; Kazuya Yamada; Ryuichi Kawamoto; Katsuhiko Kohara; Tetsuro Miki; Hideichi Makino; Haruhiko Osawa
Journal:  PLoS One       Date:  2010-03-16       Impact factor: 3.240

3.  TCF7L2 in the Go-DARTS study: evidence for a gene dose effect on both diabetes susceptibility and control of glucose levels.

Authors:  C H Kimber; A S F Doney; E R Pearson; M I McCarthy; A T Hattersley; G P Leese; A D Morris; C N A Palmer
Journal:  Diabetologia       Date:  2007-04-11       Impact factor: 10.122

Review 4.  Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis.

Authors:  Yu Tong; Ying Lin; Yuan Zhang; Jiyun Yang; Yawei Zhang; Hengchuan Liu; Ben Zhang
Journal:  BMC Med Genet       Date:  2009-02-19       Impact factor: 2.103

5.  Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.

Authors:  Camilla Noelle Rathcke; Johan Holmkvist; Torben Jørgensen; Knut Borch-Johnsen; Torben Hansen; Oluf Borbye Pedersen; Henrik Vestergaard
Journal:  PLoS One       Date:  2009-05-07       Impact factor: 3.240
  5 in total

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