Literature DB >> 16542625

Genetic epidemiology of type 1 diabetes.

Andrew D Paterson1.   

Abstract

The evidence that there is clinical heterogeneity of type 1 diabetes is reviewed and the implications for genetic studies are discussed. In the past year, genome-wide linkage analysis of 1435 multiplex families was reported. Additionally, confirmed evidence for association of specific markers at two loci (PTPN22, OAS1) as well as failure to replicate three others (IL12B, SUMO4, PAX4) is discussed. Some common themes are identified and suggestions for improvements are made. We look forward to the results from genome-wide association studies.

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Year:  2006        PMID： 16542625     DOI： 10.1007/s11892-006-0025-8

Source DB:  PubMed          Journal:  Curr Diab Rep        ISSN： 1534-4827            Impact factor:   4.810


  71 in total

Review 1.  The genetics of type 1 diabetes: lessons learned and future challenges.

Authors:  Suna Onengut-Gumuscu; Patrick Concannon
Journal:  J Autoimmun       Date:  2005-11-02       Impact factor: 7.094

2.  To: Biason-Lauber A, Boehm B, Lang-Muritano M et al. (2005) association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity. Diabetologia 48:900-905.

Authors:  A D Paterson
Journal:  Diabetologia       Date:  2005-08-13       Impact factor: 10.122

3.  Evidence that the age at diagnosis of IDDM is genetically determined.

Authors:  D Fava; S Gardner; D Pyke; R D Leslie
Journal:  Diabetes Care       Date:  1998-06       Impact factor: 19.112

4.  Rational inferences about departures from Hardy-Weinberg equilibrium.

Authors:  Jacqueline K Wittke-Thompson; Anna Pluzhnikov; Nancy J Cox
Journal:  Am J Hum Genet       Date:  2005-04-15       Impact factor: 11.025

5.  OAS1 splice site polymorphism controlling antiviral enzyme activity influences susceptibility to type 1 diabetes.

Authors:  L Leigh Field; Vagn Bonnevie-Nielsen; Flemming Pociot; Shao Lu; Thomas B Nielsen; Henning Beck-Nielsen
Journal:  Diabetes       Date:  2005-05       Impact factor: 9.461

6.  Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele.

Authors:  G Morahan; D Huang; S I Ymer; M R Cancilla; K Stephen; P Dabadghao; G Werther; B D Tait; L C Harrison; P G Colman
Journal:  Nat Genet       Date:  2001-02       Impact factor: 38.330

7.  The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom.

Authors:  A K Foulis; C N Liddle; M A Farquharson; J A Richmond; R S Weir
Journal:  Diabetologia       Date:  1986-05       Impact factor: 10.122

8.  A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

Authors:  Ann B Begovich; Victoria E H Carlton; Lee A Honigberg; Steven J Schrodi; Anand P Chokkalingam; Heather C Alexander; Kristin G Ardlie; Qiqing Huang; Ashley M Smith; Jill M Spoerke; Marion T Conn; Monica Chang; Sheng-Yung P Chang; Randall K Saiki; Joseph J Catanese; Diane U Leong; Veronica E Garcia; Linda B McAllister; Douglas A Jeffery; Annette T Lee; Franak Batliwalla; Elaine Remmers; Lindsey A Criswell; Michael F Seldin; Daniel L Kastner; Christopher I Amos; John J Sninsky; Peter K Gregersen
Journal:  Am J Hum Genet       Date:  2004-06-18       Impact factor: 11.025

9.  Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes.

Authors:  Lisa M Maier; Deborah J Smyth; Adrian Vella; Felicity Payne; Jason D Cooper; Rebecca Pask; Christopher Lowe; John Hulme; Luc J Smink; Heather Fraser; Carolyn Moule; Kara M Hunter; Giselle Chamberlain; Neil Walker; Sarah Nutland; Dag E Undlien; Kjersti S Rønningen; Cristian Guja; Constantin Ionescu-Tîrgoviste; David A Savage; David P Strachan; Laurence B Peterson; John A Todd; Linda S Wicker; Rebecca C Twells
Journal:  BMC Genet       Date:  2005-02-18       Impact factor: 2.797

10.  Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.

Authors:  Deborah Smyth; Jason D Cooper; Joanne E Collins; Joanne M Heward; Jayne A Franklyn; Joanna M M Howson; Adrian Vella; Sarah Nutland; Helen E Rance; Lisa Maier; Bryan J Barratt; Cristian Guja; Constantin Ionescu-Tîrgoviste; David A Savage; David B Dunger; Barry Widmer; David P Strachan; Susan M Ring; Neil Walker; David G Clayton; Rebecca C J Twells; Stephen C L Gough; John A Todd
Journal:  Diabetes       Date:  2004-11       Impact factor: 9.461
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  1 in total

Review 1.  Type I diabetes mellitus: genetic factors and presumptive enteroviral etiology or protection.

Authors:  Jana Precechtelova; Maria Borsanyiova; Sona Sarmirova; Shubhada Bopegamage
Journal:  J Pathog       Date:  2014-12-10
  1 in total

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